Analysis of the insertion/deletion polymorphism of the human angiotensin converting enzyme (ACE) gene in patients with renal cancer Journal Article
| Authors: | Usmani, B. A.; Janeczko, M.; Shen, R.; Mazumdar, M.; Papandreou, C. N.; Nanus, D. M. |
| Article Title: | Analysis of the insertion/deletion polymorphism of the human angiotensin converting enzyme (ACE) gene in patients with renal cancer |
| Abstract: | The angiotensin I-converting enzyme (ACE) contains an insertion/deletion (I/D) polymorphism, with the DD genotype associated with benign renal diseases. The distribution frequencies of the D and I alleles, and the DD, DI and II genotypes were determined in DNA extracted from kidney tissues of 58 renal cancer patients. The observed frequencies in patients who develop renal cancer was not significantly different than the normal population. (C) 2000 Cancer Research Campaign. |
| Keywords: | adult; controlled study; human tissue; aged; aged, 80 and over; middle aged; major clinical study; gene deletion; genotype; gene frequency; kidney neoplasms; kidney; dna; kidney cancer; gene insertion; polymorphism, genetic; mutagenesis, insertional; dna polymorphism; polymorphism; renal cancer; dipeptidyl carboxypeptidase; humans; human; male; female; priority journal; article; peptidyl-dipeptidase a; ace |
| Journal Title: | British Journal of Cancer |
| Volume: | 82 |
| Issue: | 3 |
| ISSN: | 0007-0920 |
| Publisher: | Nature Publishing Group |
| Date Published: | 2000-02-01 |
| Start Page: | 550 |
| End Page: | 552 |
| Language: | English |
| PUBMED: | 10682664 |
| PROVIDER: | scopus |
| PMCID: | PMC2363311 |
| DOI: | 10.1054/bjoc.1999.0962 |
| DOI/URL: | |
| Notes: | Source: Scopus |
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