Cytology of melanotic schwannoma in a fine needle aspirate and pleural fluid: A case report Journal Article
| Authors: | Jaffer, S.; Woodruff, J. M. |
| Article Title: | Cytology of melanotic schwannoma in a fine needle aspirate and pleural fluid: A case report |
| Abstract: | BACKGROUND: Melanotic schwannoma (MS) is a rare pigmented neural tumor most commonly occurring in the paraspinal region and involving spinal nerve roots and sympathetic ganglia. Few case reports describe the 'fine needle aspiration (FNA) cytology of MS. We report an additional case and for the first time describe the cytologic findings of MS in pleural fluid. CASE: A 44-year-old man presented with a 9.0-cm paraspinal mass associated with multiple lung nodules. FNA cytology of the paraspinal mass showed solitary and syncytially arranged spindled cells, with prominent nucleoli and variable amounts of cytoplasmic brown pigment. In pleural fluid, prominent isolated single cells were rounded and had a signet ring cell morphology. Tumor cells in both the aspirate and pleural fluid expressed S-100 protein and HMB-45. CONCLUSION: The FNA cytology findings of MS correlate well with the histologic findings. In pleural fluid, however, the cells are epithelioid, and some have a signet ring morphology, mimicking adenocarcinoma. |
| Keywords: | adult; protein expression; clinical feature; histopathology; cancer localization; case report; cancer cytodiagnosis; diagnostic value; protein s 100; pleura fluid; aspiration biopsy; melanosis; schwannoma; neurilemoma; lung nodule; aspiration cytology; cell ultrastructure; pleural fluid; human; male; priority journal; article; melanocytic schwannoma |
| Journal Title: | Acta Cytologica |
| Volume: | 44 |
| Issue: | 6 |
| ISSN: | 0001-5547 |
| Publisher: | S. Karger AG |
| Date Published: | 2000-11-01 |
| Start Page: | 1095 |
| End Page: | 1100 |
| Language: | English |
| PROVIDER: | scopus |
| PUBMED: | 11127742 |
| DOI/URL: | |
| Notes: | Export Date: 18 November 2015 -- Source: Scopus |
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