Stuck inside a cloud: Optimizing sedation to reduce ICU-associated delirium in geriatric patients Journal Article


Authors: Chen, L.; Lim, F. A.
Article Title: Stuck inside a cloud: Optimizing sedation to reduce ICU-associated delirium in geriatric patients
Abstract: Elderly population account for more than 50% of all intensive care admissions, and during their stay, up to 87% of them suffer from delirium. There is a large body of evidence demonstrating increased mortality and worse cognitive function for elderly patients who become delirious during their intensive care unit stay. Although the cause of delirium is multifactorial, inappropriate and outdated sedation methods are preventable causes. We review the current best evidences and provide what we believe are the best sedation strategies that are in line with the Society of Critical Care Medicine's Pain, Agitation and Delirium best practice guideline to reduce the incidence of intensive care unit-associated delirium. Copyright © 2015 Wolters Kluwer Health, Inc.
Keywords: mortality; drug efficacy; drug safety; liver function; gold standard; lorazepam; midazolam; opiate; delirium; sedation; practice guideline; continuous infusion; intensive care; health care cost; intensive care unit; length of stay; medical society; cognition; posttraumatic stress disorder; cognitive defect; hospital admission; morphine; drug half life; pain control; analgesia; hallucination; pain assessment; elderly; mental health; geriatric patient; fentanyl; agitation; artificial ventilation; iatrogenic disease; dexmedetomidine; care; remifentanil; delusion; intensive; benzodiazepine receptor; hypnotic agent; pain intensity; human; article; elimination half-life; deep sedation; icu-associated delirium; sedation strategies; care bundle; ventilated patient
Journal Title: Critical Care Nursing Quarterly
Volume: 38
Issue: 3
ISSN: 0887-9303
Publisher: Wolters Kluwer Health | Lippincott Williams & Wilkins  
Date Published: 2015-07-01
Start Page: 245
End Page: 252
Language: English
DOI: 10.1097/cnq.0000000000000067
PROVIDER: scopus
PUBMED: 26039646
DOI/URL:
Notes: Export Date: 2 November 2015 -- Source: Scopus
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  1. Leon Lin Chen
    52 Chen
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