Properties and clinical utility of topotecan fluorescence: Uses for retinoblastoma Journal Article


Authors: Francis, J. H.; Marr, B. P.; Schaiquevich, P.; Kellick, M. G.; Abramson, D. H.
Article Title: Properties and clinical utility of topotecan fluorescence: Uses for retinoblastoma
Abstract: Topotecan fluoresces when exposed to ultraviolet (UV) light. Our observations with UV light in retinoblastoma cases has allowed us to minimise and manage inadvertent skin contact, guide periocular injections and leakage from such injections and document conjunctival contact after periocular injection in addition to demonstrating the drug in the vitreous after intravitreal injection. The technique is safe, inexpensive and easy to perform.
Keywords: topotecan; ultraviolet radiation; clinical practice; fluorescence; retinoblastoma; patient care; human; priority journal; article; wood lamp
Journal Title: British Journal of Ophthalmology
Volume: 99
Issue: 10
ISSN: 0007-1161
Publisher: BMJ Publishing Group Ltd.  
Date Published: 2015-10-01
Start Page: 1320
End Page: 1322
Language: English
DOI: 10.1136/bjophthalmol-2015-306633
PROVIDER: scopus
PUBMED: 25926516
DOI/URL:
Notes: Export Date: 2 November 2015 -- Source: Scopus
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  1. Brian Marr
    112 Marr
  2. Jasmine Helen Francis
    256 Francis
  3. David H Abramson
    389 Abramson
  4. Michael G Kellick
    13 Kellick