TETs link hydrogen sulfide to immune tolerance Journal Article

  


Authors: Oh, S. A.; Li, M. O.
Article Title: TETs link hydrogen sulfide to immune tolerance
Abstract: Demethylation of the Foxp3 locus maintains gene expression and Treg cell stability. Yang et al. (2015) show that the gasotransmitter hydrogen sulfide co-operates with growth factor TGF-β and interleukin-2 to activate Tet-mediated DNA demethylation of Foxp3 to promote immune tolerance. © 2015 Elsevier Inc.
Keywords: unclassified drug; nonhuman; gene; interleukin 2; gene expression; transforming growth factor beta; cell protein; gene locus; dna methylation; immunological tolerance; regulatory t lymphocyte; short survey; hydrogen sulfide; demethylation; priority journal; gasotransmitter; tet protein; foxp3 gene
Journal Title: Immunity
Volume: 43
Issue: 2
ISSN: 1074-7613
Publisher: Cell Press  
Date Published: 2015-08-18
Start Page: 211
End Page: 213
Language: English
DOI: 10.1016/j.immuni.2015.08.001
PROVIDER: scopus
PUBMED: 26287675
DOI/URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-84941011904&partnerID=40&md5=002ec81ef33c6febfc0bb47e1a6089a3
Notes: Export Date: 2 October 2015 -- Source: Scopus
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MSK Authors
  1. Ming Li
    110 Li
  2. Soyoung Oh
    11 Oh
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