The myth of 0.9% saline: Neither normal nor physiological Journal Article


Author: Chen, L.
Article Title: The myth of 0.9% saline: Neither normal nor physiological
Abstract: Normal saline is the crystalloid of choice for fluid resuscitation with its utility born out of the cholera epidemic of 1832. However, its ubiquitous usage is being challenged because of a growing body of evidence suggesting that a large volume infusion of normal saline does in fact have deleterious effects on multiple body systems. Careful considerations should be given to the physiological effects of using large amounts of normal saline as one would with another pharmacological agents. © 2015 Wolters Kluwer Health, Inc. Unauthorized reproduction of this article is prohibited.
Keywords: nonhuman; immune system; ph; kidney; sodium chloride; blood clotting; crystalloid; fluid resuscitation; human; article; crystalloids; normal saline; physiological effects
Journal Title: Critical Care Nursing Quarterly
Volume: 38
Issue: 4
ISSN: 0887-9303
Publisher: Wolters Kluwer Health | Lippincott Williams & Wilkins  
Date Published: 2015-10-01
Start Page: 385
End Page: 389
Language: English
DOI: 10.1097/cnq.0000000000000084
PROVIDER: scopus
PUBMED: 26335217
DOI/URL:
Notes: Export Date: 2 October 2015 -- Source: Scopus
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  1. Leon Lin Chen
    52 Chen