Surgical management of hepatic metastases of colorectal cancer Journal Article

  


Authors: Smith, J. J.; D'Angelica, M. I.
Article Title: Surgical management of hepatic metastases of colorectal cancer
Abstract: For the 20% of patients with resectable colorectal liver metastases (CRLM), hepatic resection is safe, effective and potentially curative. Factors related to the primary and metastatic tumors individually and in clinical risk-scoring schemes are the best prognostic factors, although it is difficult to define patient groups with resectable, liver-limited CRLM that should be excluded from surgery. Systemic chemotherapy for metastatic colorectal cancer has improved but does not improve overall survival as adjuvant therapy after resection. Conversion to complete resection with systemic and/or hepatic arterial infusion chemotherapy is an appropriate goal for patients with unresectable CRLM. Copyright © 2015 Elsevier Inc. All rights reserved.
Keywords: treatment outcome; mortality; multimodality cancer therapy; liver neoplasms; combined modality therapy; cancer staging; neoplasm staging; colorectal cancer; neoplasm recurrence, local; morbidity; pathology; colorectal neoplasms; tumor recurrence; disease management; retreatment; hepatic arterial infusion; hepatic resection; secondary; colorectal liver metastasis; humans; prognosis; human
Journal Title: Hematology/Oncology Clinics of North America
Volume: 29
Issue: 1
ISSN: 0889-8588
Publisher: Elsevier Inc.  
Date Published: 2015-02-01
Start Page: 61
End Page: 84
Language: English
DOI: 10.1016/j.hoc.2014.09.003
PUBMED: 25475573
PROVIDER: scopus
DOI/URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-84938522243&partnerID=40&md5=26de783743ab9482133395ebafd85115
Notes: Export Date: 2 September 2015 -- Source: Scopus
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MSK Authors
  1. Michael D'Angelica
    777 D'Angelica
  2. Jesse Joshua Smith
    217 Smith
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