Modulation of cardiovascular toxicity in Hodgkin lymphoma: Potential role and mechanisms of aerobic training Journal Article

   


Authors: Yu, A. F.; Jones, L. W.
Article Title: Modulation of cardiovascular toxicity in Hodgkin lymphoma: Potential role and mechanisms of aerobic training
Abstract: Hodgkin lymphoma (HL) outcomes have improved due to advances in cancer treatment. However, HL survivors remain at increased risk for cardiovascular (CV) morbidity and mortality related to the long-term cardiotoxicity of HL treatment, particularly anthracycline chemotherapy and mediastinal radiotherapy. The role of aerobic training for the prevention of CV disease in the general population has been well established. However the safety and efficacy of aerobic training on CV outcomes has not been well studied in HL survivors. The purpose of this paper is to provide an up-to-date summary of the treatment-related adverse CV effects in HL survivors, review the CV benefits of exercise and review the limited evidence on the potential CV benefit of aerobic training in HL survivors. © 2015 Future Medicine Ltd.
Keywords: treatment outcome; fatigue; review; exercise; hodgkin disease; cancer survivor; heart failure; cardiotoxicity; anthracycline; ischemic heart disease; aerobic exercise; hodgkin lymphoma; modulation; valvular heart disease; mediastinal radiotherapy; human; priority journal; aerobic training
Journal Title: Future Cardiology
Volume: 11
Issue: 4
ISSN: 1479-6678
Publisher: Future Medicine  
Date Published: 2015-01-01
Start Page: 441
End Page: 452
Language: English
DOI: 10.2217/fca.15.29
PROVIDER: scopus
PUBMED: 26234325
PMCID: PMC5558532
DOI/URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-84939443073&partnerID=40&md5=5e10ae4d07109728b3db02e9e4ffff5f
Notes: Export Date: 2 September 2015 -- Source: Scopus
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MSK Authors
  1. Anthony Yu
    90 Yu
  2. Lee Winston Jones
    176 Jones
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