Total synthesis of oridamycins A and B Journal Article
| Author: | Trotta, A. H. |
| Article Title: | Total synthesis of oridamycins A and B |
| Abstract: | (Chemical Equation Presented) The total synthesis of both oridamycin A and oridamycin B was accomplished starting from a common synthetic intermediate readily prepared from geranyl acetate. The sequence utilizes an oxidative radical cyclization to construct the trans-decalin ring system, setting three of four contiguous stereocenters in one operation. The carbazole nucleus was forged through a one-pot process entailing acid-promoted dehydration followed by 6π-electrocyclization/aromatization. © 2015 American Chemical Society. |
| Journal Title: | Organic Letters |
| Volume: | 17 |
| Issue: | 13 |
| ISSN: | 1523-7060 |
| Publisher: | American Chemical Society |
| Date Published: | 2015-07-02 |
| Start Page: | 3358 |
| End Page: | 3361 |
| Language: | English |
| DOI: | 10.1021/acs.orglett.5b01629 |
| PROVIDER: | scopus |
| PUBMED: | 26069989 |
| PMCID: | PMC5606188 |
| DOI/URL: | |
| Notes: | Export Date: 3 August 2015 -- Source: Scopus |
