The Id proteins and angiogenesis Journal Article
| Authors: | Benezra, R.; Rafii, S.; Lyden, D. |
| Article Title: | The Id proteins and angiogenesis |
| Abstract: | Since the identification of the Id proteins over a decade ago, a great many cell cycle and cell fate decisions have been shown to be under the control of these proteins as described in other sections of this review issue. Perhaps the most unsuspected activity of this class of proteins has been their essential role in angiogenesis, both in the forebrain during development and during the growth and metastasis of tumors in adults. This section of the review issue will focus on the key observations which have led to these conclusions, speculations about potential mechanisms and the outlook for potential therapeutic interventions. |
| Keywords: | vasculotropin; protein expression; vascular endothelial growth factor a; unclassified drug; dna-binding proteins; proto-oncogene proteins; review; nonhuman; receptors, vascular endothelial growth factor; neoplasms; protein analysis; animals; mice; mice, knockout; bone marrow cells; vasculotropin receptor; neoplasm proteins; cell fate; cell differentiation; angiogenesis; neovascularization, pathologic; transcription factors; stem cell; endothelium cell; endothelium, vascular; dogs; hematopoietic stem cells; stem cells; inhibitor of differentiation protein 1; receptor protein-tyrosine kinases; tumor growth; neovascularization, physiologic; vascular endothelial growth factor receptor-1; forebrain; repressor proteins; precursor; blood vessels; multigene family; regulator protein; receptors, growth factor; inhibitor of differentiation protein; inhibitor of differentiation proteins; endothelial; vascular endothelial growth factors; endothelial growth factors; id; helix-loop-helix motifs; inhibitor of differentiation protein 2; humans; priority journal; lymphokines |
| Journal Title: | Oncogene |
| Volume: | 20 |
| Issue: | 58 |
| ISSN: | 0950-9232 |
| Publisher: | Nature Publishing Group |
| Date Published: | 2001-12-20 |
| Start Page: | 8334 |
| End Page: | 8341 |
| Language: | English |
| DOI: | 10.1038/sj/onc/1205160 |
| PUBMED: | 11840326 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Export Date: 21 May 2015 -- Source: Scopus |
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