Challenges of pancreatic cancer Journal Article
| Authors: | Dimastromatteo, J.; Houghton, J. L.; Lewis, J. S.; Kelly, K. A. |
| Article Title: | Challenges of pancreatic cancer |
| Abstract: | The development of novel molecular cancer imaging agents has considerably advanced in recent years. Numerous cancer imaging agents have demonstrated remarkable potential for aiding the diagnosis, staging, and treatment planning at the preclinical stage, which in turn has led to a number of agents being approved for human trials. Pancreatic ductal adenocarcinoma is currently the most deadly common carcinoma with an overall 5-year survival rate of about 6%. As detection technologies progress, the need for molecular imaging tools that will allow the diagnosis at an early stage will be crucial to improving patient outcomes. In this review, we will highlight agents that illuminate various cell populations that comprise the tumor: epithelial, endothelial, and stromal tumor cells. © 2015 Wolters Kluwer Health, Inc. |
| Keywords: | unclassified drug; review; nonhuman; pancreas cancer; cell population; molecular imaging; tumor marker; ultrasound; endothelium cell; epithelium cell; pancreas adenocarcinoma; pancreatic cancer; stroma cell; differentiation antigen; scaffold protein; osteonectin; cathepsin e; human; priority journal; claudin 4; molecular imaging agents; plectin 1; thymocyte differentiation antigen 1 |
| Journal Title: | The Cancer Journal |
| Volume: | 21 |
| Issue: | 3 |
| ISSN: | 1528-9117 |
| Publisher: | Lippincott Williams & Wilkins |
| Date Published: | 2015-05-01 |
| Start Page: | 188 |
| End Page: | 193 |
| Language: | English |
| DOI: | 10.1097/ppo.0000000000000109 |
| PROVIDER: | scopus |
| PUBMED: | 26049698 |
| PMCID: | PMC4517183 |
| DOI/URL: | |
| Notes: | Export Date: 2 July 2015 -- Source: Scopus |
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