PET imaging in renal and bladder cancers Book Section
| Authors: | Das, J. P.; Schöder, H. |
| Editor: | Signore, A. |
| Article/Chapter Title: | PET imaging in renal and bladder cancers |
| Abstract: | Diagnostic imaging of genitourinary (GU) cancers such as renal cell cancer (RCC) and bladder cancers (BCa) has evolved considerably in recent years. Whereas conventional cross-sectional imaging with computed tomography (CT) and select magnetic resonance imaging (MRI) sequences provides anatomic and morphologic information about RCC and BCa, recent developments in molecular imaging provide additional valuable data regarding metabolic activity and aggressiveness of certain tumors, as well as non-invasive information on histologic subtypes. Molecular imaging involves the use of radiotracers including Fluorine-18 (18F) fluorodeoxyglucose (FDG), carbon-11 (11C)-choline, 11C-acetate, 18F-flurothymidine, Indium-111 bevacizumab, zirconium-89 (89Zr) bevacizumab and technetium 99m methoxy isobutyl isonitrile/sestamibi (99mTc-MIBI) which may be imaged with positron emission tomography (PET) or single photon emission computed tomography (SPECT) for the diagnosis, staging, and follow-up of RCC and BCa. In addition, molecular imaging using simultaneous PET and multiplanar magnetic resonance imaging (MRI) combines the high spatial resolution and quantitative capabilities of MRI with the metabolic information obtained from PET imaging and is an emerging technology with an evolving use case for certain GU cancers. This review aims to provide an overview of the latest advances in the molecular imaging of both RCC and BCa. © 2022 Elsevier Inc. All rights reserved. |
| Keywords: | positron emission tomography; bladder cancer; renal cell cancer; genitourinary cancers; positron emission tomography/computed tomography; fluorine-18 fluorodeoxyglucose; 18f-flurothymidine; carbon-11 acetate; carbon-11 choline; pet/multiplanar magnetic resonance imaging; technetium 99m sestamibi; zirconium-89 bevacizumab |
| Book Title: | Nuclear Medicine and Molecular Imaging |
| Volume: | 3 |
| ISBN: | 978-0-12-822980-4 |
| Publisher: | Elsevier Inc. |
| Publication Place: | Amsterdam, Netherlands |
| Date Published: | 2022-01-01 |
| Start Page: | 311 |
| End Page: | 322 |
| Language: | English |
| DOI: | 10.1016/b978-0-12-822960-6.00139-3 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Book Chapter -- Chapter can be found within the section "Volume 3: Positron emission tomography studies" -- Source: Scopus |
Altmetric
Citation Impact
BMJ Impact Analytics
Related MSK Work