MLL partial tandem duplication leukemia cells are sensitive to small molecule DOT1L inhibition Journal Article


Authors: Kühn, M. W. M.; Hadler, M. J.; Daigle, S. R.; Koche, R. P.; Krivtsov, A. V.; Olhava, E. J.; Caligiuri, M. A.; Huang, G.; Bradner, J. E.; Pollock, R. M.; Armstrong, S. A.
Article Title: MLL partial tandem duplication leukemia cells are sensitive to small molecule DOT1L inhibition
Keywords: controlled study; leukemia; gene mutation; human cell; gene deletion; flow cytometry; cell proliferation; gene expression; cell growth; cell differentiation; dna methylation; chromatin immunoprecipitation; leukemia cell; acute myeloblastic leukemia; down regulation; tumor growth; mll-ptd; next generation sequencing; human; article; ic50; dot1l inhibition; pinometostat; mixed lineage leukemia; partial tandem duplication leukemia cell
Journal Title: Haematologica
Volume: 100
Issue: 5
ISSN: 0390-6078
Publisher: Ferrata Storti Foundation  
Date Published: 2015-05-01
Start Page: e190
End Page: e193
Language: English
DOI: 10.3324/haematol.2014.115337
PROVIDER: scopus
PMCID: PMC4420229
PUBMED: 25596271
DOI/URL:
Notes: Export Date: 3 June 2015 -- Source: Scopus
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  1. Scott Allen Armstrong
    108 Armstrong
  2. Michael Jason Hadler
    6 Hadler
  3. Richard Patrick Koche
    173 Koche
  4. Michael   Kuehn
    7 Kuehn