Brachytherapy for prostate cancer: Endorectal MR imaging of local treatment-related changes Journal Article
| Authors: | Coakley, F. V.; Hricak, H.; Wefer, A. E.; Speight, J. L.; Kurhanewicz, J.; Roach, M. 3rd |
| Article Title: | Brachytherapy for prostate cancer: Endorectal MR imaging of local treatment-related changes |
| Abstract: | PURPOSE: To determine the local treatment-related endorectal magnetic resonance (MR) imaging findings after brachytherapy for prostate cancer. MATERIALS AND METHODS: Endorectal MR imaging was performed in 35 consecutive patients at a mean interval of 12 months (range, 1-31 months) after brachytherapy for prostate cancer. Transverse T1-weighted and high-spatial-resolution transverse and coronal T2-weighted images were acquired. Two readers reviewed MR image quality and findings, with discrepancies resolved by consensus. Posttreatment urinary symptoms in patients (n = 24) were documented by using chart review. RESULTS: All studies were of diagnostic quality. On T2-weighted images, prostatic findings consisted of diffuse low signal intensity (n = 35) and indistinct zonal anatomy (n = 34). Intra- and extraprostatic seed locations could be distinguished. The most common extraprostatic site of seed implantation was the neurovascular bundles (n = 35, bilateral in 32). The most common extraprostatic tissue finding was increased signal intensity on T2-weighted images in the levator ani muscle (n = 34) and the genitourinary diaphragm (n = 28). Postbrachytherapy urinary symptoms showed no demonstrable correlation with periurethral or genitourinary sympphragm seed implantation or with signal intensity change in the genitourinary diaphragm. CONCLUSION: Endorectal MR imaging can be used to evaluate seed distribution and to demonstrate treatment-related changes after brachytherapy for prostate Cancer. |
| Keywords: | adult; clinical article; treatment outcome; aged; middle aged; cancer radiotherapy; nuclear magnetic resonance imaging; magnetic resonance imaging; prospective studies; prostate cancer; prostatic neoplasms; prostate; image quality; brachytherapy; cross-sectional studies; male genital tract cancer; urination disorders; humans; human; male; priority journal; article; prostate neoplasms, mr, 844.32; prostate neoplasms, therapeutic radiology, 844.12168, 844.32; radiations, injurious effects, complications of therapeutic radiology, 84.47 |
| Journal Title: | Radiology |
| Volume: | 219 |
| Issue: | 3 |
| ISSN: | 0033-8419 |
| Publisher: | Radiological Society of North America, Inc. |
| Date Published: | 2001-06-01 |
| Start Page: | 817 |
| End Page: | 821 |
| Language: | English |
| PUBMED: | 11376276 |
| PROVIDER: | scopus |
| DOI: | 10.1148/radiology.219.3.r01jn46817 |
| DOI/URL: | |
| Notes: | Export Date: 21 May 2015 -- Source: Scopus |
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