A catalog of prostate cancer nomograms Journal Article


Authors: Ross, P. L.; Scardino, P. T.; Kattan, M. W.
Article Title: A catalog of prostate cancer nomograms
Abstract: Purpose: Prediction is central to the management of prostate cancer. Nomograms are devices that make predictions. We organized many nomograms for prostate cancer. Materials and Methods: Using MEDLINE a literature search was performed on prostate cancer nomograms from January 1966 to February 2000. We recorded input variables, prediction form, the number of patients used to develop the nomogram and the outcome being predicted. We also recorded the accuracy measures reported by the original authors and whether the nomograms have withstood validation. In addition, we noted whether the nomograms were proprietary or in the public domain. Each nomogram was classified into patient clinical disease state and the outcome being predicted. Results: The literature search generated 42 published nomograms that may be applied to patients in various clinical stages of disease. Of the 42 nomograms only 18 had undergone validation, of which 2 partially failed. Few nomograms have been compared for predictive superiority and none appears to have been compared with clinical judgment alone. Conclusions: Patients with prostate cancer need accurate predictions. Prognostic nomograms are available for many clinical states and outcomes, and may provide the most accurate predictions currently available. Selection among them and progress in this field are hampered by the lack of comparisons for predictive accuracy.
Keywords: adult; aged; major clinical study; treatment planning; sensitivity and specificity; tumor localization; quality of life; prediction; biopsy; prostate cancer; prostate-specific antigen; prostatic neoplasms; prostate; probability; needle biopsy; prostate biopsy; forecasting; outcomes research; nomogram; decision support techniques; humans; prognosis; human; male; priority journal; article
Journal Title: Journal of Urology
Volume: 165
Issue: 5
ISSN: 0022-5347
Publisher: Elsevier Science, Inc.  
Date Published: 2001-05-01
Start Page: 1562
End Page: 1568
Language: English
PUBMED: 11342918
PROVIDER: scopus
DOI: 10.1016/S0022-5347(05)66349-5
DOI/URL:
Notes: Export Date: 21 May 2015 -- Source: Scopus
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  1. Peter T Scardino
    671 Scardino
  2. Michael W Kattan
    218 Kattan
  3. Phillip L Ross
    3 Ross