Overview of the cell cycle Journal Article
| Authors: | Park, M. S.; Koff, A. |
| Article Title: | Overview of the cell cycle |
| Abstract: | Progression through the cell cycle is regulated by inductive signals from outside the cell and intracellular signal pathways, while the cycle itself is regulated by cyclin-dependent kinases (CDKs). An understanding of the functions of these molecules is necessary to understand the processes of mitosis, differentiation, senescence, apoptosis, and tumorigenesis. This overview reviews the current state of knowledge for the biology of the cell-cycle, the CDKs, the role of proteolysis, targets of the cell cycle machinery, and a paradigm of cell cycle analysis. |
| Keywords: | genetics; ubiquitin; dna replication; cell cycle protein; animal; cytology; animals; cell cycle proteins; gene; cell cycle; proteasome; proteasome endopeptidase complex; physiology; cycline; eukaryotic cell; cyclin-dependent kinases; cyclins; cyclin dependent kinase; cyclin dependent kinase inhibitor; retinoblastoma protein; genes, cdc; eukaryotic cells; humans; human; article; cyclin-dependent kinase inhibitor proteins |
| Journal Title: | Current Protocols in Cell Biology |
| Volume: | 00 |
| ISSN: | 1934-2500 |
| Publisher: | John Wiley & Sons |
| Date Published: | 1998-10-01 |
| Start Page: | 8.1.1 |
| End Page: | 8.1.9 |
| Language: | English |
| PUBMED: | 18228386 |
| PROVIDER: | scopus |
| DOI: | 10.1002/0471143030.cb0801s00 |
| DOI/URL: | |
| Notes: | Export Date: 21 May 2015 -- Source: Scopus |
