Determination of metabolic monitor errors and precision under clinical conditions Journal Article


Authors: Melendez, J. A.; Veronesi, M.; Barrera, R.; Ferri, E.; Miodownik, S.
Article Title: Determination of metabolic monitor errors and precision under clinical conditions
Abstract: Background & Aims: Metabolic monitoring devices used in the critical care setting are subject to a range of conditions that may compromise their accuracy. We sought to investigate the error and precision of the Deltatrac metabolic monitor under these conditions. Methods: A modified version of the funnel burner, described by Miodownik et al. (8), was ventilated by a mechanical ventilator. This was used to examine the performance of the Deltatrac metabolic monitor over a wide range of inspired oxygen concentrations, minute ventilation, and positive end expiratory pressure at different levels of oxygen consumption and carbon dioxide production. Results: The Deltatrac measured VO2 with a mean error ± precision of 9.4% ± 19.5% (range, 9.3% ± 1.9%-72.6% ± 13.6%). The mean VCO2 error ± precision was 1.2% ± 3.1% (range-2.0% ± 1.2%-5.4% ± 3.1%). Error was significantly affected by oxygen concentration and minute ventilation but was largely independent of positive and expiratory pressure. Conclusions: The methodology of Miodownik et al. permits the expression of metabolic device errors over a wide range of simulated clinical conditions. © 2001 Harcourt Publishers Ltd.
Keywords: controlled study; methodology; sensitivity and specificity; nutritional status; accuracy; reproducibility of results; oxygen; patient monitoring; intensive care; simulation; device; oxygen consumption; validation; critical care; analytical error; carbon dioxide; methanol; monitoring, physiologic; positive end expiratory pressure; lung ventilation; oxygen concentration; ventilator; humans; article; funnel burner; indirect calorimetry; metabolic monitor; calorimetry, indirect; ventilators, mechanical
Journal Title: Clinical Nutrition
Volume: 20
Issue: 6
ISSN: 0261-5614
Publisher: Elsevier B.V.  
Date Published: 2001-12-01
Start Page: 547
End Page: 551
Language: English
DOI: 10.1054/clnu.2001.0473
PUBMED: 11884004
PROVIDER: scopus
DOI/URL:
Notes: Export Date: 21 May 2015 -- Source: Scopus
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  1. Rafael Barrera
    31 Barrera
  2. Enrico Ferri
    3 Ferri