Fludeoxyglucose positron emission tomography in the diagnosis of giant cell arteritis Journal Article
| Authors: | Turlakow, A.; Yeung, H. W. D.; Pui, J.; Macapinlac, H.; Liebovitz, E.; Rusch, V.; Goy, A.; Larson, S. M. |
| Article Title: | Fludeoxyglucose positron emission tomography in the diagnosis of giant cell arteritis |
| Abstract: | We describe a case in which fludeoxyglucose F 18 positron emission tomography (PET) led directly to the diagnosis of giant cell arteritis in an elderly woman with a fever of unknown origin. The patient presented with a 3-month history of fatigue, fever, headache, visual disturbance, jaw claudication, and anemia. A computed tomographic scan showed an anterior mediastinal mass that was suspected of being malignant. A fludeoxyglucose F 18 PET scan performed for preoperative evaluation identified striking uptake of fludeoxyglucose F 18 in the walls of the entire aorta, left main coronary artery, and subclavian, carotid, and common iliac arteries bilaterally, suggestive of an arteritis, a diagnosis subsequently confirmed by the findings of an arterial biopsy. Her erythrocyte sedimentation rate was 129 mm/h. There was normalizaton of the PET scan 2 weeks following treatment with prednisolone. This case suggests that fludeoxyglucose F 18 PET contributes to the noninvasive diagnosis of giant cell arteritis, as well as to the evaluation of the extent of disease, response to therapy, and disease recurrence. |
| Keywords: | aged; clinical feature; fatigue; case report; positron emission tomography; preoperative evaluation; radiopharmaceuticals; anemia; weight loss; tomography, x-ray computed; biopsy; prednisolone; carotid artery; fluorodeoxyglucose f 18; fluorodeoxyglucose f18; recurrent disease; headache; visual disorder; erythrocyte sedimentation rate; tomography, emission-computed; mediastinum mass; anti-inflammatory agents; iliac artery; aorta; temporal arteritis; fever of unknown origin; pyrexia idiopathica; left coronary artery; anemia, hypochromic; humans; human; female; priority journal; article; subclavian artery; claudication; giant cell arteritis; blood sedimentation |
| Journal Title: | Archives of Internal Medicine |
| Volume: | 161 |
| Issue: | 7 |
| ISSN: | 0003-9926 |
| Publisher: | American Medical Association |
| Date Published: | 2001-04-09 |
| Start Page: | 1003 |
| End Page: | 1007 |
| Language: | English |
| PUBMED: | 11295964 |
| PROVIDER: | scopus |
| DOI: | 10.1001/archinte.161.7.1003 |
| DOI/URL: | |
| Notes: | Export Date: 21 May 2015 -- Source: Scopus |
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