Management of gastric cancer Journal Article
| Authors: | Ku, G. Y.; Ilson, D. H. |
| Article Title: | Management of gastric cancer |
| Abstract: | Purpose of review: Gastric cancer is an uncommon cancer in the United States but is a very common cancer globally and is endemic in East Asia. It is a virulent cancer that presents with metastatic disease in about one half of United States patients. Recent findings: In this review article, we discuss palliative chemotherapy options as well as validated preoperative, perioperative and postoperative strategies for locally advanced disease, which include chemotherapy and/ or chemoradiation. Summary: In the metastatic setting, there has been incremental improvement in cytotoxic chemotherapy combinations in the past 2 decades. Two targeted agents - trastuzumab and ramucirumab - are now approved. In the locally advanced setting, perioperative chemotherapy or postoperative chemotherapy or chemoradiation improves outcomes relative to surgery alone. © 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins. |
| Keywords: | chemotherapy; chemoradiation; gastric cancer; adjuvant; preoperative |
| Journal Title: | Current Opinion in Gastroenterology |
| Volume: | 30 |
| Issue: | 6 |
| ISSN: | 0267-1379 |
| Publisher: | Lippincott Williams & Wilkins |
| Date Published: | 2014-10-01 |
| Start Page: | 596 |
| End Page: | 602 |
| Language: | English |
| DOI: | 10.1097/mog.0000000000000115 |
| PROVIDER: | scopus |
| PUBMED: | 25197781 |
| DOI/URL: | |
| Notes: | Export Date: 4 May 2015 -- Source: Scopus |
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