Management of gastric cancer Journal Article

Authors: Ku, G. Y.; Ilson, D. H.
Article Title: Management of gastric cancer
Abstract: Purpose of review: Gastric cancer is an uncommon cancer in the United States but is a very common cancer globally and is endemic in East Asia. It is a virulent cancer that presents with metastatic disease in about one half of United States patients. Recent findings: In this review article, we discuss palliative chemotherapy options as well as validated preoperative, perioperative and postoperative strategies for locally advanced disease, which include chemotherapy and/ or chemoradiation. Summary: In the metastatic setting, there has been incremental improvement in cytotoxic chemotherapy combinations in the past 2 decades. Two targeted agents - trastuzumab and ramucirumab - are now approved. In the locally advanced setting, perioperative chemotherapy or postoperative chemotherapy or chemoradiation improves outcomes relative to surgery alone. © 2014 Wolters Kluwer Health | Lippincott Williams & Wilkins.
Keywords: chemotherapy; chemoradiation; gastric cancer; adjuvant; preoperative
Journal Title: Current Opinion in Gastroenterology
Volume: 30
Issue: 6
ISSN: 0267-1379
Publisher: Lippincott Williams & Wilkins  
Date Published: 2014-10-01
Start Page: 596
End Page: 602
Language: English
DOI: 10.1097/mog.0000000000000115
PROVIDER: scopus
PUBMED: 25197781
Notes: Export Date: 4 May 2015 -- Source: Scopus
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MSK Authors
  1. Geoffrey Yuyat Ku
    92 Ku
  2. David H Ilson
    275 Ilson
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