Highly fluorescent sub 40-nm aminated mesoporous silica nanoparticles Journal Article

  


Authors: Suteewong, T.; Ma, K.; Drews, J. E.; Werner-Zwanziger, U.; Zwanziger, J.; Wiesner, U.; Bradbury, M. S.
Article Title: Highly fluorescent sub 40-nm aminated mesoporous silica nanoparticles
Abstract: We report the room temperature synthesis of highly fluorescent, sub-40 nm aminated mesoporous silica nanoparticles in water using triethanolamine (TEA) as catalyst. Co-condensation reactions between silica precursors, i.e., tetraethoxysilane and 3-aminopropyl triethoxysilane, allows the incorporation of amino moieties and conjugated fluorescent dye (tetramethylrhodamine-5(6)-isothiocyanate; TRITC) throughout the silica matrix. Resulting materials are characterized using a combination of transmission electron microscopy, nitrogen sorption measurements, dynamic light scattering, zeta potential measurements, thermogravimetric analysis, fluorescence correlation spectroscopy and solid-state 29Si-NMR spectroscopy. The TEA-catalyzed system leads to the formation of bright and discrete sub-40 nm aminated mesoporous silica nanoparticles with disordered pore structure and high organic content. Resulting nanomaterials may find use as simultaneous fluorescent probes and drug delivery vehicles in future theranostic applications. © 2014, Springer Science+Business Media New York.
Keywords: fluorescence; fluorescence correlation spectroscopy; nuclear magnetic resonance spectroscopy; nanoparticles; silica; fluorescence spectroscopy; amination; synthesis (chemical); drug delivery; condensation reactions; mesoporous silica; mesoporous silica nanoparticles; room temperature synthesis; mesoporous materials; transmission electron microscopy; fluorescent; silanes; resulting materials; thermogravimetric analysis; ethanolamines; drug delivery vehicles; zeta potential measurements
Journal Title: Journal of Sol-Gel Science and Technology
Volume: 74
Issue: 1
ISSN: 0928-0707
Publisher: Springer  
Date Published: 2015-04-01
Start Page: 32
End Page: 38
Language: English
DOI: 10.1007/s10971-014-3567-2
PROVIDER: scopus
DOI/URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-84925507319&partnerID=40&md5=8d2a99610c69d28261f764183e7b0862
Notes: Export Date: 4 May 2015 -- Source: Scopus
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MSK Authors
  1. Michelle S Bradbury
    65 Bradbury
  2. Teeraporn Suteewong
    2 Suteewong
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