Computed tomographic features predictive of local recurrence in patients with early stage lung cancer treated with stereotactic body radiation therapy Journal Article

   

Authors:	Halpenny, D.; Ridge, C. A.; Hayes, S.; Zheng, J.; Moskowitz, C. S.; Rimner, A.; Ginsberg, M. S.
Article Title:	Computed tomographic features predictive of local recurrence in patients with early stage lung cancer treated with stereotactic body radiation therapy
Abstract:	Introduction: The objective of this study is to identify computed tomography (CT) features of local recurrence (LR) after stereotactic body radiation therapy (SBRT) for lung cancer. Methods: Two hundred eighteen patients underwent SBRT for lung cancer from January 1st, 2006 to March 1st, 2011. Signs of LR recorded: opacity with new bulging margin, opacification of air bronchograms, enlarging pleural effusion, new or enlarging mass, and increased lung density at the treatment site. Results: A new bulging margin at the treatment site was the only feature significantly associated with LR (P<. .005). Conclusion: Most CT features classically associated with LR following conventional radiation therapy are unreliable for predicting LR following SBRT. © 2015 Elsevier Inc.
Keywords:	adult; aged; middle aged; major clinical study; cancer recurrence; cancer staging; follow up; computer assisted tomography; image analysis; radiotherapy; lung cancer; computerized tomography; tomography; pleura effusion; patient treatment; stereotactic body radiation therapy; biological organs; diseases; computed tomography; non small cell lung cancer; computed tomography scanner; local recurrence; pleural effusion; computed tomographic; very elderly; human; priority journal; article; conventional radiation therapy; early-stage lung cancers; treatment sites
Journal Title:	Clinical Imaging
Volume:	39
Issue:	2
ISSN:	0899-7071
Publisher:	Elsevier Inc.
Date Published:	2015-03-01
Start Page:	254
End Page:	258
Language:	English
DOI:	10.1016/j.clinimag.2014.12.005
PROVIDER:	scopus
PUBMED:	25571791
PMCID:	PMC4547627
DOI/URL:	http://www.scopus.com/inward/record.url?eid=2-s2.0-84926132207&partnerID=40&md5=2087ddaf415e29781cdda62624c2eac3
Notes:	Export Date: 4 May 2015 -- Source: Scopus

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