Human lymphocytes sensitized to HLA A0201 and HLA A2402 binding WT-1 peptides loaded on autologous cytokine activated monocytes or EBV transformed B cells yield HLA restricted WT-1 peptide specific cytotoxic T cells that lyse primary WT-1+leukemic cells in vitro and, in vivo, home to and induced regression of WT-1+leukemic xenografts bearing the restricting HLA alleles Meeting Abstract
| Authors: | Doubrovina, E.; Guerrero, J.; Lee, S. Y.; Koehne, G.; Doubrovin, M.; Diaz-Barrientos, T.; O'Reilly, R. J. |
| Abstract Title: | Human lymphocytes sensitized to HLA A0201 and HLA A2402 binding WT-1 peptides loaded on autologous cytokine activated monocytes or EBV transformed B cells yield HLA restricted WT-1 peptide specific cytotoxic T cells that lyse primary WT-1+leukemic cells in vitro and, in vivo, home to and induced regression of WT-1+leukemic xenografts bearing the restricting HLA alleles |
| Meeting Title: | 44th Annual Meeting of the American Society of Hematology (ASH) |
| Journal Title: | Blood |
| Volume: | 100 |
| Issue: | 11 Pt. 1 |
| Meeting Dates: | 2002 Dec 6-10 |
| Meeting Location: | Philadelphia, PA |
| ISSN: | 0006-4971 |
| Publisher: | American Society of Hematology |
| Date Published: | 2002-11-01 |
| Start Page: | 615A |
| End Page: | 616A |
| Language: | English |
| ACCESSION: | WOS:000179184702426 |
| PROVIDER: | wos |
| PUBMED: | 12448415 |
| Notes: | Meeting Abstract: 2424 -- 44th Annual Meeting of the American-Society-of-Hematology -- DEC 06-10, 2002 -- PHILADELPHIA, PENNSYLVANIA -- 1 -- Source: Wos |
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