Novel targeted therapies in diffuse large B-cell lymphoma Journal Article
| Authors: | Mehta-Shah, N; Younes, A. |
| Article Title: | Novel targeted therapies in diffuse large B-cell lymphoma |
| Abstract: | Diffuse large B-cell lymphoma (DLBCL) is the most common aggressive non-Hodgkin's lymphoma. Next-generation sequencing techniques have improved our understanding of the molecular pathways that may drive oncogenesis. Many novel classes of drugs are in development that may improve the treatment of DLBCL, either as single agents or in combination, that exploit their synergy to overcome resistance. We review the key novel targets and therapeutics in the treatment of DLBCL, including immunomodulatory agents and immunotherapy. © 2015. |
| Journal Title: | Seminars in Hematology |
| Volume: | 52 |
| Issue: | 2 |
| ISSN: | 0037-1963 |
| Publisher: | W.B. Saunders Co-Elsevier Inc. |
| Date Published: | 2015-04-01 |
| Start Page: | 126 |
| End Page: | 137 |
| Language: | English |
| DOI: | 10.1053/j.seminhematol.2015.01.007 |
| PROVIDER: | scopus |
| PUBMED: | 25805592 |
| DOI/URL: | |
| Notes: | Export Date: 2 April 2015 -- Source: Scopus |
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