Promising novel agents for aggressive B-cell lymphoma Journal Article


Author: Younes, A.
Article Title: Promising novel agents for aggressive B-cell lymphoma
Abstract: Diffuse large B-cell lymphoma (DLBCL) is the most common type of lymphoma in the western world. Current treatment regimens result in curing approximately 50% to 60% of patients with DLBCL. In 2006, the Food and Drug Administration approved rituximab for use in the first-line treatment of patients with DLBCL in combination with anthracycline-based chemotherapy regimens. Since then, no other agents have been approved for the treatment of DLBCL. This article reviews recent data on the most promising agents in development for the treatment of DLBCL. © 2016 Elsevier Inc.
Keywords: diffuse large b-cell lymphoma; b-cell receptor; bcl2 inhibitor; ezh2 inhibitor
Journal Title: Hematology/Oncology Clinics of North America
Volume: 30
Issue: 6
ISSN: 0889-8588
Publisher: Elsevier Inc.  
Date Published: 2016-12-01
Start Page: 1229
End Page: 1237
Language: English
DOI: 10.1016/j.hoc.2016.07.007
PROVIDER: scopus
PUBMED: 27888877
PMCID: PMC5576035
DOI/URL:
Notes: Review -- Export Date: 3 January 2017 -- Source: Scopus
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  1. Anas Younes
    319 Younes