Gender disparities in hematuria evaluation and bladder cancer diagnosis: A population based analysis Journal Article


Authors: Garg, T.; Pinheiro, L. C.; Atoria, C. L.; Donat, S. M.; Weissman, J. S.; Herr, H. W.; Elkin, E. B.
Article Title: Gender disparities in hematuria evaluation and bladder cancer diagnosis: A population based analysis
Abstract: Purpose Men are diagnosed with bladder cancer at 3 times the rate of women. However, women present with advanced disease and have poorer survival, suggesting delays in bladder cancer diagnosis. Hematuria is the presenting symptom in most cases. We assessed gender differences in hematuria evaluation in older adults with bladder cancer. Materials and Methods Using the SEER (Surveillance, Epidemiology and End Results) cancer registry linked with Medicare claims we identified Medicare beneficiaries 66 years old or older diagnosed with bladder cancer between 2000 and 2007 with a claim for hematuria in the year before diagnosis. We examined the impact of gender, and demographic and clinical factors on time from initial hematuria claim to urology visit and on time from initial hematuria claim to hematuria evaluation, including cystoscopy, upper urinary tract imaging and urine cytology. Results Of 35,646 patients with a hematuria claim in the year preceding bladder cancer diagnosis 97% had a urology visit claim. Mean time to urology visit was 27 days (range 0 to 377). Time to urology visit was longer for women than for men (adjusted HR 0.9, 95% CI 0.87-0.92). Women were more likely to undergo delayed (after greater than 30 days) hematuria evaluation (adjusted OR 1.13, 95% CI 1.07-1.21). Conclusions We observed longer time to a urology visit for women than for men presenting with hematuria. These findings may explain stage differences in bladder cancer diagnosis and inform efforts to decrease gender disparities in bladder cancer stage and outcomes.
Keywords: treatment outcome; aged; major clinical study; cancer staging; cancer diagnosis; demography; disease association; bladder cancer; urinary bladder neoplasms; hematuria; medicare; urine incontinence; comorbidity; cancer registry; seer program; consultation; sex difference; prostate hypertrophy; cystoscopy; urine retention; quality of health care; urinary tract; urine cytology; human; male; female; priority journal; article
Journal Title: Journal of Urology
Volume: 192
Issue: 4
ISSN: 0022-5347
Publisher: Elsevier Science, Inc.  
Date Published: 2014-10-01
Start Page: 1072
End Page: 1077
Language: English
DOI: 10.1016/j.juro.2014.04.101
PROVIDER: scopus
PMCID: PMC4260395
PUBMED: 24835058
DOI/URL:
Notes: Export Date: 2 March 2015 -- Source: Scopus
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MSK Authors
  1. Sherri M Donat
    174 Donat
  2. Elena B Elkin
    163 Elkin
  3. Tullika Garg
    7 Garg
  4. Harry W Herr
    594 Herr
  5. Coral Lynn Atoria
    51 Atoria