A SEER-medicare population-based study of lymphedema-related claims incidence following breast cancer in men Journal Article


Authors: Reiner, A. S.; Jacks, L. M.; Van Zee, K. J.; Panageas, K. S.
Article Title: A SEER-medicare population-based study of lymphedema-related claims incidence following breast cancer in men
Abstract: Each year there are an estimated 200,000 new breast cancer cases diagnosed in the United States; of these, 1% of cases are in men. Lymphedema can be a devastating complication from breast cancer and its treatment. Currently, almost all lymphedema-related research is based on women and extrapolated to men. We conducted the first population-based study of men with incident breast cancer of any stage, diagnosed from 1998 to 2005, who were 65 years and older in the Surveillance, Epidemiology, and End Results (SEER)-Medicare linked database. We utilized claims related to lymphedema and lymphedema treatment in our cohort. We defined 'lymphedema-specific' claims to contain the word 'lymphedema' in the Medicare claim description; similarly, 'lymphedema-related' claims were defined as treatments reimbursed for lymphedema but not necessarily containing the word 'lymphedema' in the Medicare claim description. We identified 628 men with incident breast cancer from 1998 to 2005 who were 65 years and older. The cumulative incidence, censored for deaths, of lymphedema-specific claims at 2, 3, 4, and 5 years was 8.0, 9.2, 10.5, and 10.5%, respectively. The median follow-up was 3.4 years and for those without any event was 4.7 years. The cumulative incidence, censored for deaths, of lymphedema-related claims at 2, 3, 4, and 5 years was 26.9, 32.2, 35.4, and 39.8%. Rates for men were similar to analogous rates for women. Lymphedema is a common complication affecting men with breast cancer as well as women and appropriate treatment and rehabilitation strategies need to be implemented for both genders. © Springer Science+Business Media, LLC. 2011.
Keywords: aged; major clinical study; cancer staging; follow up; cancer diagnosis; cancer incidence; breast cancer; data base; cancer mortality; lymphedema; medicare; reimbursement; cancer registry; age distribution; population based case control study; men; population-based; seer
Journal Title: Breast Cancer Research and Treatment
Volume: 130
Issue: 1
ISSN: 0167-6806
Publisher: Springer  
Date Published: 2011-11-01
Start Page: 301
End Page: 306
Language: English
DOI: 10.1007/s10549-011-1649-1
PROVIDER: scopus
PUBMED: 21735047
DOI/URL:
Notes: --- - "Export Date: 3 January 2012" - "CODEN: BCTRD" - "Source: Scopus"
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  1. Anne S Reiner
    248 Reiner
  2. Kimberly J Van Zee
    293 Van Zee
  3. Katherine S Panageas
    512 Panageas