Visualization of orbital involvement of Erdheim-Chester disease on PET/CT Journal Article


Authors: Beylergil, V.; Carrasquillo, J. A.; Hyman, D. M.; Diamond, E. L.
Article Title: Visualization of orbital involvement of Erdheim-Chester disease on PET/CT
Abstract: We report a 58-year-old man who presented with swelling and redness in his left eye, headache, and blurred vision. A contrast-enhanced CT of the orbits revealed bilateral orbital masses. Whole-body PET/CT showed bilateral retrobulbar hypermetabolic soft tissue lesions, multiple areas of soft tissue involvement, and osseous lesions in bilateral lower extremities. An open surgical biopsy of the left orbital mass revealed xanthomatous non-Langerhans histiocytic infiltrate with Touton giant cells, positive for CD68 but negative for CD1a, establishing a diagnosis of Erdheim-Chester disease.
Keywords: case report; positron emission tomography; computer assisted tomography; tomography, x-ray computed; pathology; biopsy; positron-emission tomography; scintiscanning; surgery; radiography; orbit; multimodal imaging; humans; human; male; erdheim-chester disease
Journal Title: Clinical Nuclear Medicine
Volume: 39
Issue: 7
ISSN: 0363-9762
Publisher: Lippincott Williams & Wilkins  
Date Published: 2014-07-01
Start Page: 660
End Page: 661
Language: English
DOI: 10.1097/RLU.0000000000000452
PUBMED: 24873784
PROVIDER: scopus
DOI/URL:
Notes: Export Date: 2 March 2015 -- Source: Scopus
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  1. David Hyman
    354 Hyman
  2. Eli Louis Diamond
    203 Diamond