Randomized clinical trials in pancreatic cancer Journal Article


Authors: Stojadinovic, A.; Hoos, A.; Brennan, M. F.; Conlon, K. C. P.
Article Title: Randomized clinical trials in pancreatic cancer
Abstract: The authors reviewed 59 prospective, randomized, controlled trials for pancreatic carcinoma that were published between 1977 and 2000. Of the 11 surgical trials, two each studied extent of resection (standard versus pylorus-preserving pancreaticoduodenectomy) and lymphadenectomy (standard versus extended lymph node dissection), five trials compared different types of pancreaticenteric reconstruction, and one each evaluated the role of prophylactic gastrojejunostomy and chemical splanchnicectomy in the setting of advanced disease.
Keywords: cancer chemotherapy; controlled study; cancer surgery; clinical trial; review; doxorubicin; fluorouracil; gemcitabine; cancer radiotherapy; pancreas cancer; pancreatic neoplasms; prospective studies; evidence-based medicine; lymphadenectomy; cancer immunotherapy; controlled clinical trial; randomized controlled trial; randomized controlled trials; medical oncology; mitomycin c; octreotide; gastrojejunostomy; humans; human
Journal Title: Surgical Oncology Clinics of North America
Volume: 11
Issue: 1
ISSN: 1055-3207
Publisher: Elsevier Inc.  
Date Published: 2002-01-01
Start Page: 207
End Page: 229
Language: English
DOI: 10.1016/s1055-3207(03)00082-6
PUBMED: 11930875
PROVIDER: scopus
DOI/URL:
Notes: Export Date: 14 November 2014 -- Source: Scopus
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  1. Murray F Brennan
    1059 Brennan
  2. Axel Hoos
    28 Hoos
  3. Kevin C Conlon
    120 Conlon