Randomized clinical trials in advanced and metastatic colorectal carcinoma Journal Article

  


Authors: D'Angelica, M. I.; Shoup, M. C.; Nissan, A.
Article Title: Randomized clinical trials in advanced and metastatic colorectal carcinoma
Abstract: The treatment of advanced colorectal cancer has long been a dilemna for clinicians. After many years of therapy limited to 5-fluorouracil (5-FU)-based chemotherapy, a number of new discoveries have significantly advanced this field in the last decade. The advent of irinotecan has given us hope for a second line chemotherapeutic agent and a possible new combination for first line chemotherapy.
Keywords: cancer chemotherapy; controlled study; cancer surgery; clinical trial; review; cisplatin; fluorouracil; interferon; drug efficacy; liver neoplasms; methotrexate; follow up; prospective studies; evidence-based medicine; controlled clinical trial; antimetabolites, antineoplastic; randomized controlled trial; cyclophosphamide; dexamethasone; irinotecan; colorectal carcinoma; colorectal neoplasms; randomized controlled trials; folinic acid; medical oncology; mitomycin c; floxuridine; gastrointestinal disease; hepatic artery; semustine; humans; human
Journal Title: Surgical Oncology Clinics of North America
Volume: 11
Issue: 1
ISSN: 1055-3207
Publisher: Elsevier Inc.  
Date Published: 2002-01-01
Start Page: 173
End Page: 191
Language: English
DOI: 10.1016/s1055-3207(03)00080-2
PUBMED: 11928799
PROVIDER: scopus
DOI/URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-0036135120&partnerID=40&md5=bb90ba53aae5b74d8f173d5d52e7e94e
Notes: Export Date: 14 November 2014 -- Source: Scopus
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MSK Authors
  1. Margaret Shoup
    20 Shoup
  2. Aviram Nissan
    20 Nissan
  3. Michael D'Angelica
    780 D'Angelica
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