D-lactic acidosis mediated neuronal encephalopathy in acute lymphoblastic leukemia patient: An under diagnosis Journal Article


Authors: Mendu, D. R.; Fleisher, M.; Mccash, S. I.; Pessin, M. S.; Ramanathan, L. V.
Article Title: D-lactic acidosis mediated neuronal encephalopathy in acute lymphoblastic leukemia patient: An under diagnosis
Abstract: Background: D-lactic acidosis, also referred as D-lactate encephalopathy, has been reported in patients with short bowl syndrome (SBS). Case report: The neurologic symptoms include altered mental status, slurred speech, and ataxia. Onset of neurological symptoms is accompanied by metabolic acidosis and high anion gap. We present here a case of D-lactic acidosis in a patient with acute lymphoblastic leukemia (ALL) who developed severe neurological symptoms and metabolic acidosis due to vancomycin-resistant enterococci (VRE) infection, and elevated D-lactic acid.
Keywords: human tissue; aged; case report; doxorubicin; methotrexate; rituximab; nuclear magnetic resonance imaging; cd34 antigen; neuropathy; myalgia; cyclophosphamide; vincristine; acute lymphoblastic leukemia; abdominal pain; dizziness; fever; hospitalization; prednisolone; bone marrow biopsy; hla dr antigen; brain disease; emergency care; urinalysis; vancomycin resistant enterococcus; linezolid; mental health; cd19 antigen; enterococcal infection; cd30 antigen; lactic acid; gait disorder; cefepime; metabolic acidosis; hematological malignancy; human; female; article; slurred speech; d-lactic acid; neuronal encephalopathy d lactic acidosis
Journal Title: Clinica Chimica Acta
Volume: 441
ISSN: 0009-8981
Publisher: Elsevier Science BV  
Date Published: 2015-02-20
Start Page: 90
End Page: 91
Language: English
DOI: 10.1016/j.cca.2014.12.025
PROVIDER: scopus
PUBMED: 25542530
DOI/URL:
Notes: Export Date: 2 February 2015 -- Source: Scopus
Altmetric
Citation Impact
BMJ Impact Analytics
MSK Authors
  1. Martin Fleisher
    312 Fleisher
  2. Samuel Isaac McCash
    13 McCash
  3. Damodara Rao Mendu
    4 Mendu