Prevention of post-operative delirium in older patients with cancer undergoing surgery Journal Article


Authors: Korc-Grodzicki, B.; Root, J. C.; Alici, Y.
Article Title: Prevention of post-operative delirium in older patients with cancer undergoing surgery
Abstract: Prevention has been shown to be the most effective strategy for minimizing the occurrence of delirium as well as delirium-associated complications.5 Therefore prevention of delirium in older adults undergoing surgery is a top research priority given the extent of the problem in this patient population. In this review, we will describe the POD syndrome, previously identified risk factors that predict POD in surgical cancer patients, long-term outcomes of POD and both non-pharmacologic and pharmacologic therapies aimed at preventing POD.
Keywords: surgical technique; constipation; drug activity; review; placebo; drug efficacy; side effect; treatment duration; cancer patient; outcome assessment; infection; multiple cycle treatment; dehydration; aripiprazole; chlorpromazine; donepezil; haloperidol; olanzapine; quetiapine; risperidone; rivastigmine; delirium; extrapyramidal symptom; qt prolongation; sedation; cohort analysis; exercise; practice guideline; risk factor; high risk patient; age; hypoxia; cost effectiveness analysis; health program; cause of death; hospitalization; disease severity; training; cardiovascular disease; surgical risk; comorbidity; catheterization; single drug dose; atypical antipsychotic agent; neuroleptic agent; surgery; malignant neoplastic disease; vision; health promotion; cognitive defect; antiinflammatory activity; antioxidant activity; hearing; heart arrhythmia; infection prevention; drug contraindication; postoperative pain; hydration; visual impairment; oxygen saturation; oxygenation; drug protein binding; polypharmacy; health education; antihistaminic agent; artificial ventilation; orthopedic surgery; elective surgery; dexmedetomidine; nutrition; central nervous system disease; noise reduction; randomized controlled trial (topic); falling; mini mental state examination; torsade des pointes; mobilization; orientation; cholinesterase inhibitor; cholinergic receptor blocking agent; melatonin; knee surgery; reorientation; postoperative delirium; alpha 2 adrenergic receptor stimulating agent; white matter lesion; hip surgery; cancer; human; melatonin receptor agonist; ramelteon; dependent personality disorder; dsm-5; hospital elder life program; preoperative pain; sleep pattern
Journal Title: Journal of Geriatric Oncology
Volume: 6
Issue: 1
ISSN: 1879-4068
Publisher: Elsevier Inc.  
Date Published: 2015-01-01
Start Page: 60
End Page: 69
Language: English
DOI: 10.1016/j.jgo.2014.10.002
PROVIDER: scopus
PUBMED: 25454768
PMCID: PMC5627364
DOI/URL:
Notes: Export Date: 2 February 2015 -- Source: Scopus
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  1. Yesne Alici
    94 Alici
  2. James Charles Root
    113 Root