Assessment of patient-reported clinical outcome in pancreatic and other hepatobiliary cancers: The FACT Hepatobiliary Symptom Index Journal Article
| Authors: | Yount, S.; Cella, D.; Webster, K.; Heffernan, N.; Chang, C. H.; Odom, L.; Van Gool, R. |
| Article Title: | Assessment of patient-reported clinical outcome in pancreatic and other hepatobiliary cancers: The FACT Hepatobiliary Symptom Index |
| Abstract: | This study's aim was to develop and validate a symptom index derived from the Functional Assessment of Cancer Therapy-Hepatobiliary, a questionnaire measuring general and hepatobiliary disease specific aspects of quality of life. The item pool was narrowed to 26 questions that assess symptoms and function. Each of 95 hepatobiliary cancer experts narrowed the list to 5 of the most important to attend to when treating advanced hepatobiliary disease. Eight symptoms were endorsed by more than 20% of the experts (3 pain, 2 fatigue, nausea, weight loss, jaundice) and were named the FACT-Hepatobiliary Symptom Index-8 (FHSI-8). Among 51 hepatobiliary cancer patients, the FHSI-8 showed good internal consistency (0.79), test-retest reliability (r = 0.86), strong association with mood (r = -0.56), and patient differentiation by ECOG Performance Status Rating ( P < 0.0001) and treatment status ( P = 0.057). Symptom scaling in diseases such as hepatobiliary cancer is feasible and may provide an efficient, clinically-relevant endpoint for following groups over time. © U.S. Cancer Pain Relief Committee, 2002. |
| Keywords: | adult; controlled study; aged; aged, 80 and over; middle aged; major clinical study; fatigue; liver neoplasms; pancreatic neoplasms; quality of life; nausea; weight reduction; cancer pain; pancreas carcinoma; mood; severity of illness index; jaundice; rating scale; reliability; bile duct carcinoma; bile duct neoplasms; symptomatology; self assessment (psychology); symptoms; hepatobiliary cancer; cancer; humans; human; male; female; article |
| Journal Title: | Journal of Pain and Symptom Management |
| Volume: | 24 |
| Issue: | 1 |
| ISSN: | 0885-3924 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2002-07-01 |
| Start Page: | 32 |
| End Page: | 44 |
| Language: | English |
| DOI: | 10.1016/s0885-3924(02)00422-0 |
| PUBMED: | 12183093 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Export Date: 14 November 2014 -- Source: Scopus |
