Granulomatous and suppurative dermatitis at interferon alfa injection sites: Report of 2 cases Journal Article
| Authors: | Sanders, S.; Busam, K.; Tahan, S. R.; Johnson, R. A.; Sachs, D. |
| Article Title: | Granulomatous and suppurative dermatitis at interferon alfa injection sites: Report of 2 cases |
| Abstract: | It has previously been reported that interferon alfa injection sites may develop pyoderma gangrenosum, interface dermatitis, vasculitis, or, more commonly, ulcers characterized by intravascular thrombi and a mixed inflammatory cell infiltrate. We describe 2 patients in whom granulomatous and suppurative dermatitis developed at interferon alfa injection sites. These cases extend the spectrum of interferon alfa injection site reactions. The histologic and clinical similarities of these cases with pyoderma gangrenosum and cutaneous Crohn's disease are explored. |
| Keywords: | adult; middle aged; histopathology; case report; alpha interferon; cell infiltration; inflammatory cell; injections, subcutaneous; skin diseases; injection site; granuloma; pyoderma gangrenosum; clinical examination; interferon-alpha; skin inflammation; thrombus; vasculitis; humans; human; male; female; priority journal; article; suppurative dermatitis; suppuration |
| Journal Title: | Journal of the American Academy of Dermatology |
| Volume: | 46 |
| Issue: | 4 |
| ISSN: | 0190-9622 |
| Publisher: | Mosby Elsevier |
| Date Published: | 2002-04-01 |
| Start Page: | 611 |
| End Page: | 616 |
| Language: | English |
| DOI: | 10.1067/mjd.2002.119087 |
| PUBMED: | 11907520 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Export Date: 14 November 2014 -- Source: Scopus |
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