Quality of virtual colonoscopy in patients who have undergone radiation therapy or surgery: How successful are we? Journal Article


Authors: Gollub, M. J.; Ginsberg, M. S.; Cooper, C.; Thaler, H. T.
Article Title: Quality of virtual colonoscopy in patients who have undergone radiation therapy or surgery: How successful are we?
Abstract: OBJECTIVE. In patients who have a history of abdominopelvic radiation, surgery, or both, conventional colonoscopy may fail to examine the entire colon. The purpose of this study is to assess whether high-quality virtual colonoscopy can be achieved in this patient population. MATERIALS AND METHODS. After colonic cleansing, 61 patients (16 men and 45 women; mean age, 64 years; age range, 27-81 years) underwent 63 virtual colonoscopy examinations after using either single- or multidetector CT (slice thickness, 3.75-5.0 mm; table speed, 1.7-11.25 cm/sec; pitch, 1.5-3.0; and overlapped reconstructions, 1.95-2.5 cm) in supine and prone positions after IV administration of 1 mg of glucagon and rectal air insufflation. Conventional two-dimensional axial images were analyzed on a PACS (picture archiving and communication system) workstation. Two radiologists, who were unaware of patient history, independently evaluated the colonic distention on a 4-point scale (4 = optimal distention) and fluid retention on a 3-point scale (3 = no fluid) for all segments of the colon in patients who were imaged in both the supine and prone positions. Segmental and total average colon scores were calculated. RESULTS. Forty-one patients (65%; 43 examinations, 67%) underwent prior surgery, radiation, or both (surgery, n = 29; radiation, n = 3; both, n = 11). The average overall colonic distention and fluid retention for this group was 3.13 and 2.38, respectively, versus 3.24 and 2.3 in the control group (p = not significant). CONCLUSION. High-quality examinations were achieved in patients who had previously undergone radiation, surgery, or both with no clinically significant difference in distention or fluid retention compared with the controls.
Keywords: adult; controlled study; aged; aged, 80 and over; middle aged; cancer surgery; major clinical study; cancer radiotherapy; pelvis; sensitivity and specificity; quality control; computer assisted tomography; image analysis; image interpretation, computer-assisted; colonic neoplasms; abdomen; colonoscopy; population risk; pelvic neoplasms; scoring system; rating scale; body posture; pitch; image reconstruction; colonography, computed tomographic; fluid retention; velocity; abdominal neoplasms; virtual reality; thickness; colon dilatation; supine position; humans; human; male; female; priority journal; article; colon lavage
Journal Title: American Journal of Roentgenology
Volume: 178
Issue: 5
ISSN: 0361-803X
Publisher: American Roentgen Ray Society  
Date Published: 2002-05-01
Start Page: 1109
End Page: 1116
Language: English
PUBMED: 11959711
PROVIDER: scopus
DOI/URL:
Notes: Export Date: 14 November 2014 -- Source: Scopus
Citation Impact
MSK Authors
  1. Marc J Gollub
    208 Gollub
  2. Michelle S Ginsberg
    235 Ginsberg
  3. Howard T Thaler
    245 Thaler
  4. Cathleen A Cooper
    5 Cooper