Factors associated with pneumothorax and pneumothorax requiring treatment after percutaneous lung biopsy in 443 consecutive patients Journal Article

  

Authors:	Covey, A. M.; Gandhi, R.; Brody, L. A.; Getrajdman, G.; Thaler, H. T.; Brown, K. T.
Article Title:	Factors associated with pneumothorax and pneumothorax requiring treatment after percutaneous lung biopsy in 443 consecutive patients
Abstract:	PURPOSE: To describe patient- and procedure-related factors associated with post-biopsy pneumothorax and those that require intervention. MATERIALS AND METHODS: Patient and procedure data from all lung biopsies performed at a single center between January 2000 and July 2001 were recorded prospectively. Data included patient demographics, lesion size, lesion depth from skin, needle size, number of passes, patient position during biopsy, imaging method used (computed tomography/ fluoroscopy), if sedation was used, occurrence of pneumothorax and whether the pneumothorax required treatment. Patient charts were retrospectively reviewed to determine smoking history, as well as previous ipsilateral chest surgery or radiation therapy. Univariate and multivariate analysis was performed, and P < .05 was considered significant. RESULTS: Four-hundred fifty-three biopsies were performed on 443 patients. One-hundred six patients (23.4%) had post-biopsy pneumothorax and 31 patients (6.8% overall, 29.2% of pneumothorax group) required intervention. By univariate analysis, increased patient age, smaller lesion size, increased depth from skin, supine position, and no history of surgery were significant predictors of biopsy-related pneumothorax. However, only increased patient age, supine position, no history of ipsilateral surgery, and history of smoking were associated with pneumothorax that required intervention. By multivariate analysis, increased patient age, smaller lesion size, and no history of surgery predicted pneumothorax; supine position, history of smoking, and no history of ipsilateral surgery predicted which patients with pneumothorax would require treatment. CONCLUSION: Independent risk factors for pneumothorax include increased patient age, smaller lesion size, and no history of surgery. Previous surgery and prone positioning during biopsy appear to provide a "protective effect" against clinically significant post-biopsy pneumothorax.
Keywords:	adult; controlled study; aged; aged, 80 and over; middle aged; surgical technique; retrospective studies; major clinical study; prospective study; prospective studies; computer assisted tomography; tumor volume; lung neoplasms; radiotherapy; sedation; risk factors; smoking; tomography, x-ray computed; diagnostic imaging; retrospective study; risk factor; age; pneumothorax; biopsy, needle; lung; multivariate analysis; sex factors; body posture; posture; analysis of variance; lung biopsy; thorax surgery; percutaneous biopsy; fluoroscopy; supine position; humans; human; male; female; priority journal; article; percutaneous lung biopsy
Journal Title:	Journal of Vascular and Interventional Radiology
Volume:	15
Issue:	5
ISSN:	1051-0443
Publisher:	Elsevier Science, Inc.
Date Published:	2004-05-01
Start Page:	479
End Page:	483
Language:	English
PROVIDER:	scopus
PUBMED:	15126658
DOI:	10.1097/01.RVI.0000124951.24134.50
DOI/URL:	http://www.scopus.com/inward/record.url?eid=2-s2.0-2342588136&partnerID=40&md5=5706ff4c6e268f7b217e10acac846bc4
Notes:	J. Vasc. Intervent. Radiol. -- Cited By (since 1996):45 -- Export Date: 16 June 2014 -- CODEN: JVIRE C2 - 15126658 -- Source: Scopus

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