Authors: | Bearman, G.; Vaamonde, C.; Larone, D.; Drusin, L.; Zuccotti, G. |
Article Title: | Pseudo-outbreak of multi-drug-resistant Mycobacterium tuberculosis associated with presumed laboratory processing contamination |
Abstract: | An investigation prompted by six positive cultures for multi-drug-resistant Mycobacterium tuberculosis during a 7-week period found that an unusual resistance pattern, temporal proximity of laboratory processing, and identical DNA fingerprints supported the theory of cross-contamination. Laboratory processing procedures included specimen batching and multi-use vials of buffer solution. Processing procedures were changed and no additional cases of suspected cross-contamination have been observed. |
Keywords: | adult; clinical article; genetics; united states; methodology; laboratory diagnosis; aspiration; standard; mycobacterium tuberculosis; specimen handling; new york city; dna fingerprinting; microbiology; bacterial dna; bacterium culture; isolation and purification; microbiological examination; antibiotic sensitivity; lung biopsy; multidrug resistance; tuberculosis; cross infection; epidemic; disease outbreaks; contamination; microbiological techniques; humans; human; article; hospital laboratory; sputum analysis; tuberculosis, multidrug-resistant |
Journal Title: | Infection Control and Hospital Epidemiology |
Volume: | 23 |
Issue: | 10 |
ISSN: | 0899-823X |
Publisher: | The Society for Healthcare Epidemiology of America |
Date Published: | 2002-10-01 |
Start Page: | 620 |
End Page: | 622 |
Language: | English |
PUBMED: | 12400894 |
PROVIDER: | scopus |
DOI: | 10.1086/501982 |
DOI/URL: | |
Notes: | Export Date: 14 November 2014 -- Source: Scopus |