Treatment options for stage I nonseminoma Journal Article


Author: Feldman, D. R.
Article Title: Treatment options for stage I nonseminoma
Abstract: Three weeks ago, a healthy 29-year-old man underwent a left orchiectomy for a left testis mass revealing a 3-cm mixed nonseminomatous germ cell tumor composed of embryonal carcinoma and teratoma. Lymphovascular invasion was identified (Fig 1), but there was no invasion into the rete testis or other structures. Preoperative α-fetoprotein was elevated at 42 ng/mL but normalized to 3.5 ng/mL postoperatively. Human chorionic gonadotropin and lactate dehydrogenase were normal both before and after orchiectomy. A computed tomography scan of the chest, abdomen, and pelvis with contrast obtained 1 week ago revealed no evidence of retroperitoneal adenopathy or other sites of metastatic disease. The patient presents to see his physician, eager to discuss his treatment options and make a decision between adjuvant treatment and surveillance.
Keywords: cancer survival; treatment outcome; survival rate; overall survival; cancer recurrence; cisplatin; cancer combination chemotherapy; systemic therapy; cancer adjuvant therapy; recurrence risk; follow up; antineoplastic agent; lymph node dissection; etoposide; bleomycin; embryonal carcinoma; retrograde ejaculation; recurrence free survival; disease surveillance; randomized controlled trial (topic); testis nonseminoma cancer; human; article
Journal Title: Journal of Clinical Oncology
Volume: 32
Issue: 34
ISSN: 0732-183X
Publisher: American Society of Clinical Oncology  
Date Published: 2014-12-01
Start Page: 3797
End Page: 3800
Language: English
DOI: 10.1200/jco.2014.56.8006
PROVIDER: scopus
PUBMED: 25366681
DOI/URL:
Notes: Export Date: 2 January 2015 -- Source: Scopus
Altmetric
Citation Impact
BMJ Impact Analytics
MSK Authors
  1. Darren Richard Feldman
    340 Feldman