Use of CT perfusion to discriminate between brain metastases from different primaries Journal Article
| Authors: | Dolgushin, M. B.; Pronin, I. N.; Holodny, E. A.; Fadeeva, L. M.; Holodny, A. I.; Kornienko, V. N. |
| Article Title: | Use of CT perfusion to discriminate between brain metastases from different primaries |
| Abstract: | Thirty-six metastases in 22 patients were studied prospectively using computed tomography perfusion. Regions of interests were drawn around: the enhancing part of the tumor, necrotic central part, periphery, peritumoral edema, and normal white matter. Cerebral blood volume, cerebral blood flow, and mean transit time were calculated for each zone. The enhancing part of the tumor significantly differed from the other zones in 11 of 12. Metastases of different primaries can be differentiated from one another with statistically significance (P<.05) by at least one perfusion parameter in 57% of cases. |
| Keywords: | adult; clinical article; aged; prospective study; edema; melanoma; computer assisted tomography; ovary cancer; breast cancer; differential diagnosis; lung cancer; histology; computerized tomography; colon cancer; brain metastasis; kidney cancer; blood volume; brain blood flow; iodinated contrast medium; uterus sarcoma; white matter; computed tomography; brain tumors; brain metastases; perfusion; computed tomography scanner; tumor necrosis; ct perfusion; human; article |
| Journal Title: | Clinical Imaging |
| Volume: | 39 |
| Issue: | 1 |
| ISSN: | 0899-7071 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2015-01-01 |
| Start Page: | 9 |
| End Page: | 14 |
| Language: | English |
| DOI: | 10.1016/j.clinimag.2014.10.006 |
| PROVIDER: | scopus |
| PUBMED: | 25457544 |
| DOI/URL: | |
| Notes: | Export Date: 2 January 2015 -- Source: Scopus |
