A prospective trial comparing pain and quality of life measures after anatomic lung resection using thoracoscopy or thoracotomy Journal Article
| Authors: | Rizk, N. P.; Ghanie, A.; Hsu, M.; Bains, M. S.; Downey, R. J.; Sarkaria, I. S.; Finley, D. J.; Adusumilli, P. S.; Huang, J.; Sima, C. S.; Burkhalter, J. E.; Park, B. J.; Rusch, V. W. |
| Article Title: | A prospective trial comparing pain and quality of life measures after anatomic lung resection using thoracoscopy or thoracotomy |
| Abstract: | Background. Minimally invasive lung lobectomy and segmentectomy by video-assisted thoracic surgery (VATS) are assumed to result in better quality of life and less postoperative pain compared with standard open approaches. To date, few prospective studies have compared the two approaches. We performed a prospective cohort study to compare quality of life and pain scores during the first 12 months after VATS or open anatomic resection. Methods. Patients were prospectively enrolled from May 2009 to April 2012. Patients with clinical stage I lung cancer who were scheduled to undergo anatomic lungm resection were eligible. The Brief Pain Index and Medical Outcomes Study 36-Item Short Form Health Survey were conducted perioperatively and at four assessments during the first 12 months after the operation. Intent-to-treat analyses using mixed-effects models were used to longitudinally assess the effect of treatment on quality of life components (physical component summary and mental component summary) and pain. Results. In total, 74 patients underwent thoracotomy, and 132 underwent VATS (including 19 patients who were converted to thoracotomy); 40 and 80 patients, respectively, completed the 12-month surveys. Baseline characteristics were similar between the two groups. Physical component summary and Brief Pain Index scores were similar between the two groups throughout the 12 months of followup. The mental component summary score, however, was consistently worse in the VATS group. Conclusions. Patient-reported physical component summary and pain scores after VATS and thoracotomy were similar during the first 12 months after surgical resection. |
| Keywords: | adult; cancer chemotherapy; controlled study; aged; cancer surgery; major clinical study; cancer recurrence; postoperative period; conference paper; comparative study; cancer staging; follow up; antineoplastic agent; prospective study; quality of life; thoracotomy; cohort analysis; lung cancer; postoperative complication; length of stay; urinary tract infection; short form 36; analgesia; postoperative pain; heart atrium fibrillation; thoracoscopy; video assisted thoracoscopic surgery; named inventories, questionnaires and rating scales; brief pain inventory; intention to treat analysis; human; male; female; brief pain index; medical outcomes study |
| Journal Title: | Annals of Thoracic Surgery |
| Volume: | 98 |
| Issue: | 4 |
| ISSN: | 0003-4975 |
| Publisher: | Elsevier Science, Inc. |
| Date Published: | 2014-10-01 |
| Start Page: | 1160 |
| End Page: | 1166 |
| Language: | English |
| DOI: | 10.1016/j.athoracsur.2014.05.028 |
| PROVIDER: | scopus |
| PUBMED: | 25086945 |
| PMCID: | PMC4307383 |
| DOI/URL: | |
| Notes: | Export Date: 1 December 2014 -- Source: Scopus |
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