From molecular understanding to clinical advances Journal Article


Authors: Lee, C. H.; Motzer, R. J.
Article Title: From molecular understanding to clinical advances
Abstract: Big data and computational biology brought to the forefront a number of potential actionable mutations and drug targets in clear cell renal cell carcinoma in 2013. As we continue to unravel the molecular underpinnings of tumorigenesis and progression, the clinical benefits will eventually be reaped.
Keywords: note; animal; metabolism; animals; metastasis; transcription factor; pathology; kidney carcinoma; kidney neoplasms; transcription factors; kidney tumor; carcinoma, renal cell; von hippel lindau protein; receptors, cxcr4; hypoxia inducible factor 1; chemokine receptor cxcr4; hypoxia-inducible factor 1; von hippel-lindau tumor suppressor protein; humans; human
Journal Title: Nature Reviews Urology
Volume: 11
Issue: 2
ISSN: 1759-4812
Publisher: Nature Publishing Group  
Date Published: 2014-02-01
Start Page: 77
End Page: 79
Language: English
PUBMED: 24366347
PROVIDER: scopus
DOI: 10.1038/nrurol.2013.307
DOI/URL:
Notes: Export Date: 1 December 2014 -- Source: Scopus
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  1. Robert Motzer
    1243 Motzer
  2. Chung-Han   Lee
    157 Lee