Authors: | Lee, C. H.; Motzer, R. J. |
Article Title: | From molecular understanding to clinical advances |
Abstract: | Big data and computational biology brought to the forefront a number of potential actionable mutations and drug targets in clear cell renal cell carcinoma in 2013. As we continue to unravel the molecular underpinnings of tumorigenesis and progression, the clinical benefits will eventually be reaped. |
Keywords: | note; animal; metabolism; animals; metastasis; transcription factor; pathology; kidney carcinoma; kidney neoplasms; transcription factors; kidney tumor; carcinoma, renal cell; von hippel lindau protein; receptors, cxcr4; hypoxia inducible factor 1; chemokine receptor cxcr4; hypoxia-inducible factor 1; von hippel-lindau tumor suppressor protein; humans; human |
Journal Title: | Nature Reviews Urology |
Volume: | 11 |
Issue: | 2 |
ISSN: | 1759-4812 |
Publisher: | Nature Publishing Group |
Date Published: | 2014-02-01 |
Start Page: | 77 |
End Page: | 79 |
Language: | English |
PUBMED: | 24366347 |
PROVIDER: | scopus |
DOI: | 10.1038/nrurol.2013.307 |
DOI/URL: | |
Notes: | Export Date: 1 December 2014 -- Source: Scopus |