The Journal of Pathology 2008 Jeremy Jass Prize for Research Excellence in Pathology Journal Article
| Authors: | Hall, P. A.; Poulsom, R.; Coates, P. J.; Du, M. Q.; Hogendoorn, P. C. W.; Jones, L. J.; Ladanyi, M.; Murray, G. I.; Niedobitek, G. |
| Article Title: | The Journal of Pathology 2008 Jeremy Jass Prize for Research Excellence in Pathology |
| Abstract: | The first Jass Prize for Research Excellence has been awarded to a group from Hannover in Germany. These authors discovered the epigenetic inactivation of microRNA gene hsa-mir-9-1 in human breast cancer and characterized its biological and clinical relevance. This frequent epigenetic silencing was found to occur early in the development of breast cancer, and illustrates another mechanism by which tumour development is influenced by genes that operate without expression as proteins. Copyright © 2009 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd. |
| Keywords: | protein expression; gene mutation; promoter region; review; breast cancer; microrna; breast; gene function; breast neoplasms; dna methylation; gene expression regulation; epigenetics; epigenesis, genetic; medical research; gene repression; gene control; gene inactivation; gene silencing; micrornas; periodicals as topic; jass; research prize; awards and prizes; regulatory rna sequence; pathology, molecular |
| Journal Title: | Journal of Pathology |
| Volume: | 219 |
| Issue: | 4 |
| ISSN: | 0022-3417 |
| Publisher: | Wiley Blackwell |
| Date Published: | 2009-12-01 |
| Start Page: | 393 |
| End Page: | 395 |
| Language: | English |
| DOI: | 10.1002/path.2634 |
| PUBMED: | 19852036 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Export Date: 30 November 2010" - "CODEN: JPTLA" - "Source: Scopus" |
