In vivo dosimetry and seed localization in prostate brachytherapy with permanent implants Conference Paper


Authors: Rosenfeld, A. B.; Brady, J.; Braddock, T.; Pervertailo, V.; Cutajar, D. L.; Lerch, M. L. F.; Takacs, G. J.; Bucci, J.; Kersley, J.; Zaider, M.; Zelefsky, M.
Editor: Metzler, S. D.
Title: In vivo dosimetry and seed localization in prostate brachytherapy with permanent implants
Conference Title: 2003 IEEE Nuclear Science Symposium, Medical Imaging Conference
Abstract: This paper reports on the development of an interactive, intraoperative dose planning system for seed implant brachytherapy in cancer treatment This system involves in-vivo dosimetry and the ability to determine implanted seed positions. The first stage of this project is the development of a urethral alarm probe to measure the dose along the urethra during a prostate brachytherapy treatment procedure. Ultimately the system will be used to advise the physicians upon reaching a preset dose rate or dose after total seed decay in urethra during the seed placement. The second stage is the development of a method and instrumentation for in-vivo measurements of the location of implanted seeds in the same frame as for dose planning, and using these in intraoperative treatment planning. We have developed a silicon mini-detector and preamplifier/amplifier system to satisfy the spectroscopic requirements of the urethral probe. This technique will avoid complications related to overdosing the urethra and the rectum.
Keywords: radiotherapy; tumors; dosimetry; radical prostatectomy; toxicity; urethra; silicon; implants (surgical); spectroscopic analysis; seed localization; project management; prostrate brachytherapy; amplifiers (electronic)
Journal Title IEEE Nuclear Science Symposium Conference Record
Volume: 3
Conference Dates: 2003 Oct 19-25
Conference Location: Portland, OR
ISBN: 1095-7863
Publisher: IEEE  
Date Published: 2003-01-01
Start Page: 1594
End Page: 1598
Language: English
PROVIDER: scopus
DOI: 10.1109/NSSMIC.2003.1352182
DOI/URL:
Notes: IEEE Nucl. Sci. Symp. Conf. Rec. -- Conference code: 64189 -- Export Date: 25 September 2014 -- CODEN: 85OQA -- 19 October 2003 through 25 October 2003 -- Source: Scopus
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  1. Michael J Zelefsky
    754 Zelefsky
  2. Marco Zaider
    171 Zaider