Authors: | Hurria, A.; Kris, M. G. |
Article Title: | Management of lung cancer in older adults |
Abstract: | Lung cancer is the leading cause of cancer death in the United States. At the time of diagnosis, most patients are older than 65 years and have Stage III or IV disease. More than 80% of patients have non-small cell lung cancer and the rest have small cell lung cancer. Age is not a significant prognostic factor for overall survival and response to treatment for patients with either type of lung cancer. Treatment options should be tailored to older patients based on the same selection process and benefits seen in the population as a whole. This article reviews the available data regarding surgery, radiation, and systemic treatment for older patients with lung cancer and considers the role of geriatric assessment in the evaluation of older patients. © American Cancer Society, 2003. |
Keywords: | cancer survival; controlled study; treatment outcome; aged; aged, 80 and over; surgical technique; neutropenia; review; cisplatin; doxorubicin; patient selection; united states; gemcitabine; paclitaxel; cancer radiotherapy; combined modality therapy; cancer staging; nutritional status; medical decision making; carboplatin; quality of life; infection; anemia; etoposide; esophagitis; kidney disease; leukopenia; lung lobectomy; lung non small cell cancer; lung resection; nausea; thrombocytopenia; antineoplastic combined chemotherapy protocols; lung neoplasms; pneumonectomy; radiotherapy; weight reduction; cyclophosphamide; vincristine; medical assessment; cancer mortality; age; docetaxel; irinotecan; dyspnea; postoperative complication; drug fatality; psychological aspect; social support; lung small cell cancer; health status; comorbidity; gefitinib; brain metastasis; muscle weakness; cognition; mental disease; nausea and vomiting; medical specialist; intermethod comparison; aging; lung surgery; navelbine; alopecia; neurologic disease; elderly care; hearing impairment; patient care planning; physical capacity; drug use; hematologic disease; cooperation; geriatric assessment; geriatric care; individualization; humans; prognosis; human; male; female; priority journal |
Journal Title: | CA - A Cancer Journal for Clinicians |
Volume: | 53 |
Issue: | 6 |
ISSN: | 0007-9235 |
Publisher: | Wiley-Blackwell |
Date Published: | 2003-11-01 |
Start Page: | 325 |
End Page: | 341 |
Language: | English |
PUBMED: | 15224973 |
PROVIDER: | scopus |
DOI: | 10.3322/canjclin.53.6.325 |
DOI/URL: | |
Notes: | Export Date: 25 September 2014 -- Source: Scopus |