MR imaging of the ipsilateral breast in women with percutaneously proven breast cancer Journal Article

Authors: Liberman, L.; Morris, E. A.; Dershaw, D. D.; Abramson, A. F.; Tan, L. K.
Article Title: MR imaging of the ipsilateral breast in women with percutaneously proven breast cancer
Abstract: OBJECTIVE. The purpose of this study was to review MR imaging findings in the ipsilateral breast in women with percutaneously proven breast cancer. MATERIALS AND METHODS. Retrospective review was performed of records of 70 consecutive women with percutaneously proven unilateral breast cancer who were considered candidates for breast conservation surgery and who had preoperative MR imaging of the ipsilateral breast. MR images and medical records were reviewed. RESULTS. MR imaging identified mammographically and clinically occult cancer other than the index lesion in the ipsilateral breast in 19 women (27%), including infiltrating cancer in 11 women (16%) and ductal carcinoma in situ in eight women (11%). These additional sites of cancer were in the same quadrant as the index cancer in 14 women (20%), in a different quadrant in three women (4%), and in both the same and different quadrants in two women (3%). Additional sites of cancer were more likely in women with, rather than in those without, a family history of breast cancer (42% vs 14%, p < 0.02) and in women whose index cancer was infiltrating lobular rather than other histologies (55% vs 22%, p < 0.06). In 17 women (24%), MR imaging detected ipsilateral lesions that were benign. Changes due to prior percutaneous biopsy were infrequently observed on MR images and included a clip in 12 women (17%) and a small hematoma in two women (3%). CONCLUSION. MR imaging identified additional sites of ipsilateral cancer in 27% of women with percutaneously proven breast cancer. The yield was highest in women with a family history of breast cancer or infiltrating lobular histology in the index cancer. Change after biopsy was infrequent and did not interfere with the MR imaging interpretation.
Keywords: adult; controlled study; aged; middle aged; retrospective studies; major clinical study; cancer localization; cancer staging; nuclear magnetic resonance imaging; magnetic resonance imaging; cancer diagnosis; preoperative evaluation; image analysis; breast; breast neoplasms; retrospective study; mammography; biopsy, needle; family history; cancer infiltration; breast carcinoma; medical record; reliability; cancer classification; hematoma; neoplasms, multiple primary; carcinoma, intraductal, noninfiltrating; percutaneous biopsy; carcinoma, ductal, breast; carcinoma, lobular; ultrasonography, mammary; humans; human; female; priority journal; article
Journal Title: American Journal of Roentgenology
Volume: 180
Issue: 4
ISSN: 0361-803X
Publisher: American Roentgen Ray Society  
Date Published: 2003-04-01
Start Page: 901
End Page: 910
Language: English
PUBMED: 12646427
PROVIDER: scopus
Notes: Export Date: 12 September 2014 -- Source: Scopus