Radiation safety in the treatment of patients with thyroid diseases by radioiodine 131I: Practice recommendations of the american thyroid association Journal Article


Authors: Sisson, J. C.; Freitas, J.; McDougall, I. R.; Dauer, L. T.; Hurley, J. R.; Brierley, J. D.; Edinboro, C. H.; Rosenthal, D.; Thomas, M. J.; Wexler, J. A.; Asamoah, E.; Avram, A. M.; Milas, M.; Greenlee, C.
Article Title: Radiation safety in the treatment of patients with thyroid diseases by radioiodine 131I: Practice recommendations of the american thyroid association
Abstract: Background: Radiation safety is an essential component in the treatment of patients with thyroid diseases by 131I. The American Thyroid Association created a task force to develop recommendations that would inform medical professionals about attainment of radiation safety for patients, family members, and the public. The task force was constituted so as to obtain advice, experience, and methods from relevant medical specialties and disciplines. Methods: Reviews of Nuclear Regulatory Commission regulations formed the basic structure of recommendations. Members of the task force contributed both ideas and methods that are used at their respective institutions to aid groups responsible for treatments and that instruct patients and caregivers in the attainment of radiation safety. There are insufficient data on long-term outcomes to create evidence-based guidelines. Results: The information was used to compile delineations of radiation safety. Factors and situations that govern implementation of safety practices are cited and discussed. Examples of the development of tables to ascertain the number of hours or days (24-hour cycles) of radiation precaution appropriate for individual patients treated with 131I for hyperthyroidism and thyroid cancer have been provided. Reminders in the form of a checklist are presented to assist in assessing patients while taking into account individual circumstances that would bear on radiation safety. Information is presented to supplement the treating physician's advice to patients and caregivers on precautions to be adopted within and outside the home. Conclusion: Recommendations, complying with Nuclear Regulatory Commission regulations and consistent with guidelines promulgated by the National Council on Radiation Protection and Measurement (NCRP-155), can help physicians and patients maintain radiation safety after treatment with 131I of patients with thyroid diseases. Both treating physicians and patients must be informed if radiation safety, an integral part of therapy with 131I, is to be attained. Based on current regulations and understanding of radiation exposures, recommendations have been made to guide physicians and patients in safe practices after treatment with radioactive iodine. © Copyright 2011, Mary Ann Liebert, Inc.
Keywords: treatment duration; outcome assessment; evidence based medicine; patient assessment; practice guideline; radiation exposure; iodine 131; pregnancy; caregiver; thyroid cancer; drug half life; hyperthyroidism; hypothyroidism; radiation safety; health care organization; drug contraindication; photon; health care planning; thyrotropin; government regulation; follitropin; thyroid disease; thyroxine; thyrotropin blood level; checklist; euthyroidism; thyroxine blood level
Journal Title: Thyroid
Volume: 21
Issue: 4
ISSN: 1050-7256
Publisher: Mary Ann Liebert, Inc  
Date Published: 2011-04-01
Start Page: 335
End Page: 346
Language: English
DOI: 10.1089/thy.2010.0403
PROVIDER: scopus
PUBMED: 21417738
DOI/URL:
Notes: --- - "Export Date: 23 June 2011" - "CODEN: THYRE" - "Source: Scopus"
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  1. Lawrence Dauer
    170 Dauer