Leptomeningeal metastases from recurrent squamous cell cancer of the skin Journal Article

  


Authors: Begemann, M.; Rosenblum, M. K.; Loh, J.; Kraus, D.; Raizer, J. J.
Article Title: Leptomeningeal metastases from recurrent squamous cell cancer of the skin
Abstract: We report two patients with leptomeningeal metastases from squamous cell cancer of the skin. In one patient cauda equina metastases appeared 6 years after initial presentation; the tumor from radical neck dissection demonstrated perineural invasion suggesting a possible route for subarachnoid dissemination. The other patient presented 2 years after initial diagnosis with confusion and cranial nerve seven and twelve palsies. Both patients died from complications of leptomeningeal metastases.
Keywords: adult; aged; middle aged; cancer surgery; clinical feature; anamnesis; case report; neck dissection; squamous cell carcinoma; carcinoma, squamous cell; cancer radiotherapy; gadolinium; methotrexate; drug megadose; nuclear magnetic resonance imaging; recurrent cancer; magnetic resonance imaging; cancer diagnosis; cytology; skin biopsy; skin neoplasms; skin cancer; weight reduction; cancer mortality; cancer invasion; confusion; cerebrospinal fluid; lumbar puncture; meningeal neoplasms; spinal cord; drug response; muscle weakness; craniotomy; perineurium; cancer classification; fatal outcome; cranial nerve paralysis; disease exacerbation; facial nerve paralysis; visual impairment; perineural invasion; peripheral nervous system neoplasms; meningeal metastasis; eye surgery; central nervous system disease; leptomeningeal metastases; tendon reflex; cauda equina; subarachnoid space; squamous cell cancer; vibration sense; neurological complications; humans; prognosis; human; male; article; hypoglossal nerve
Journal Title: Journal of Neuro-Oncology
Volume: 63
Issue: 3
ISSN: 0167-594X
Publisher: Springer  
Date Published: 2003-07-01
Start Page: 295
End Page: 298
Language: English
DOI: 10.1023/a:1024328215432
PUBMED: 12892236
PROVIDER: scopus
DOI/URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-0038637256&partnerID=40&md5=3bbd5e79fc9849d3ddd84983da7b8b8c
Notes: Export Date: 12 September 2014 -- Source: Scopus
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MSK Authors
  1. John Loh
    2 Loh
  2. Dennis Kraus
    268 Kraus
  3. Jeffrey J Raizer
    22 Raizer
  4. Marc Rosenblum
    424 Rosenblum
  5. Martin Begemann
    5 Begemann
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