Peripheral blood progenitor cell mobilization for autologous and allogeneic hematopoietic cell transplantation: Guidelines from the American Society for Blood and Marrow Transplantation Journal Article


Authors: Duong, H. K.; Savani, B. N.; Copelan, E.; Devine, S.; Costa, L. J.; Wingard, J. R.; Shaughnessy, P.; Majhail, N.; Perales, M. A.; Cutler, C. S.; Bensinger, W.; Litzow, M. R.; Mohty, M.; Champlin, R. E.; Leather, H.; Giralt, S.; Carpenter, P. A.
Article Title: Peripheral blood progenitor cell mobilization for autologous and allogeneic hematopoietic cell transplantation: Guidelines from the American Society for Blood and Marrow Transplantation
Abstract: Peripheral blood progenitor cell mobilization practices vary significantly among institutions. Effective mobilization regimens include growth factor alone, chemotherapy and growth factor combined, and, more recently, incorporation of plerixafor with either approach. Many institutions have developed algorithms to improve stem cell mobilization success rates and cost-effectiveness. However, an optimal stem cell mobilization regimen has not been defined. Practical guidelines are needed to address important clinical questions, including which growth factor is optimal, what chemotherapy and dose is most effective, and when to initiate leukapheresis. We present recommendations, based on a comprehensive review of the literature, from the American Society of Blood and Marrow Transplantation. Ā© 2014 American Society for Blood and Marrow Transplantation.
Keywords: peripheral blood; hematopoietic transplantation; progenitor cell mobilization
Journal Title: Biology of Blood and Marrow Transplantation
Volume: 20
Issue: 9
ISSN: 1083-8791
Publisher: Elsevier Inc.  
Date Published: 2014-09-01
Start Page: 1262
End Page: 1273
Language: English
DOI: 10.1016/j.bbmt.2014.05.003
PROVIDER: scopus
PUBMED: 24816581
DOI/URL:
Notes: Export Date: 2 September 2014 -- CODEN: BBMTF -- Source: Scopus
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  1. Sergio Andres Giralt
    1050 Giralt
  2. Miguel-Angel Perales
    913 Perales