Authors: | Garg, K.; Soslow, R. A. |
Article Title: | Familial tumors of the uterine corpus |
Abstract: | Women with Lynch syndrome are at considerable risk for developing endometrial carcinoma, but current screening guidelines for detection of Lynch syndrome focus almost exclusively on colorectal carcinoma. Lynch syndrome associated colorectal and endometrial carcinomas have some important differences with implications for screening strategies. These differences are discussed in this review, along with the most effective screening criteria and testing methods for detection of Lynch syndrome in endometrial carcinoma patients. © 2011 Elsevier Inc. |
Keywords: | gene mutation; clinical feature; histopathology; review; cancer risk; endometrium carcinoma; disease association; cancer screening; practice guideline; colorectal carcinoma; microsatellite instability; familial cancer; hnpcc; lynch syndrome; familial endometrial carcinoma |
Journal Title: | Surgical Pathology Clinics |
Volume: | 4 |
Issue: | 1 |
ISSN: | 1875-9181 |
Publisher: | Elsevier Inc. |
Date Published: | 2011-03-01 |
Start Page: | 243 |
End Page: | 259 |
Language: | English |
DOI: | 10.1016/j.path.2010.12.002 |
PROVIDER: | scopus |
DOI/URL: | |
Notes: | --- - "Export Date: 23 June 2011" - "Source: Scopus" |