MYC, MAX, and small cell lung cancer Journal Article
| Authors: | Rudin, C. M.; Poirier, J. T. |
| Article Title: | MYC, MAX, and small cell lung cancer |
| Abstract: | In this issue of Cancer Discovery, Romero and colleagues identify somatic mutations and deletions of MAX, and also define what seem to be mutually exclusive alterations in MYC family members and other MYC-associated factors in small cell lung cancer. Taken together, these data highlight the importance of MYC signaling in small cell lung cancer and suggest possible avenues for therapeutic intervention. © 2014 American Association for Cancer Research. |
| Keywords: | signal transduction; protein expression; somatic mutation; gene deletion; gene amplification; protein p53; neuroendocrine tumor; oncogene; lung small cell cancer; tumor growth; pheochromocytoma; oncogene myc; brg1 protein; exome; human; article; max gene |
| Journal Title: | Cancer Discovery |
| Volume: | 4 |
| Issue: | 3 |
| ISSN: | 2159-8274 |
| Publisher: | American Association for Cancer Research |
| Date Published: | 2014-03-01 |
| Start Page: | 273 |
| End Page: | 274 |
| Language: | English |
| DOI: | 10.1158/2159-8290.cd-14-0069 |
| PROVIDER: | scopus |
| PUBMED: | 24596200 |
| DOI/URL: | |
| Notes: | Export Date: 1 August 2014 -- Source: Scopus |
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