Tumor ablation for treatment of colorectal liver metastases Journal Article
| Authors: | Leung, U.; Fong, Y. |
| Article Title: | Tumor ablation for treatment of colorectal liver metastases |
| Abstract: | As the treatment options for colorectal liver metastases continue to expand, ablation has been integrated into the multidisciplinary management of this disease. Following the success of earlier modalities such as cryotherapy and radiofrequency ablation, more options have emerged, including use of microwaves, irreversible electroporation, laser therapy, and focused ultrasound. Indications have also widened from unresectable disease to include treatment with curative intent, often in combination with surgery and systemic and regional therapies. Randomized evidence is relatively lacking overall, but there are ample retrospective data to support the use of ablation. Good patient selection is important, and the treating clinician must understand the strengths and weaknesses of each modality to ensure safety and maximize efficacy. In this review, we discuss the principles of the more commonly used ablation techniques and summarize the evidence, with emphasis on recent data. © 2014 Springer Science+Business Media New York. |
| Keywords: | cancer chemotherapy; liver neoplasms; prospective study; morbidity; retrospective study; cancer mortality; colorectal neoplasms; high intensity focused ultrasound; electroporation; hyperthermic therapy; cryoablation; radiofrequency ablation; catheter ablation; cryosurgery; laser therapy; microwaves; microwave therapy; tumor ablation; radiofrequency catheter ablation; colorectal liver metastasis; human; article; high-intensity focused ultrasound ablation; laser induced interstitial thermotherapy |
| Journal Title: | Current Colorectal Cancer Reports |
| Volume: | 10 |
| Issue: | 2 |
| ISSN: | 1556-3790 |
| Publisher: | Springer |
| Date Published: | 2014-06-01 |
| Start Page: | 239 |
| End Page: | 248 |
| Language: | English |
| DOI: | 10.1007/s11888-014-0214-9 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Export Date: 1 August 2014 -- Source: Scopus |
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